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Scholar Results 1 - 10 of about 35 citing Chan: Diabetes impairs hypothalamo-pituitary-adrenal (HPA) responses to hypoglycemia, and.... (0.09 sec) 

Hypothalamic control of energy balance: different peptides, different functions

- rockefeller.edu [PDF] 
SF Leibowitz, KE Wortley - Peptides, 2004 - Elsevier
Energy balance is maintained via a homeostatic system involving both the brain
and the periphery. A key component of this system is the hypothalamus. Over the
past two decades, major advances have been made in identifying an ...
Cited by 104 - Related articles - All 7 versions

The selfish brain: competition for energy resources

- voeljemens.nl [PDF] 
A Peters, U Schweiger, L Pellerin, C Hubold, … - Neuroscience and biobehavioral reviews, 2004 - Elsevier
The brain occupies a special hierarchical position in the organism. It is
separated from the general circulation by the blood-brain barrier, has high
energy consumption and a low energy storage capacity, uses only specific ...
Cited by 97 - Related articles - All 8 versions

Hyperactivation of the hypothalamo-pituitary-adrenocortical axis in streptozotocin-diabetes …


O Chan, K Inouye, M Vranic, SG Matthews - Endocrinology, 2002 - Endocrine Soc
Although increased hypothalamo-pituitary-adrenocortical (HPA) activity has been
reported in diabetic patients, the mechanisms underlying hyperactivation are
still unclear. We investigated whether alterations in pituitary, adrenal ...
Cited by 34 - Related articles - BL Direct - All 5 versions

Diabetes-related changes in cAMP-dependent protein kinase activity and decrease in …

- physiology.org
T Matsumoto, K Wakabayashi, T Kobayashi, … - American Journal of Physiology- Heart and Circulatory …, 2004 - Am Physiological Soc
Using superior mesenteric artery rings isolated from age-matched controls and
streptozotocin (STZ)-induced diabetic rats, we recently demonstrated that
EDHF-type relaxation is impaired in STZ-induced diabetic rats, possibly due ...
Cited by 31 - Related articles - BL Direct - All 7 versions

Effects of recurrent hyperinsulinemia with and without hypoglycemia on counterregulation in …

- physiology.org
K Inouye, K Shum, O Chan, J Mathoo, SG … - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc
To understand the mechanisms whereby recurrent hypoglycemia increases the risk
of subsequent hypoglycemia, it was necessary to differentiate the effects of
recurrent hyperinsulinemia from those of hyperinsulinemic hypoglycemia. We ...
Cited by 19 - Related articles - BL Direct - All 4 versions

Insulin alone increases hypothalamo-pituitary-adrenal activity, and diabetes lowers peak …

- endojournals.org
O Chan, K Inouye, E Akirav, E Park, MC … - Endocrinology, 2005 - Endocrine Soc
Diabetes is associated with increased basal hypothalamo-pituitary-adrenal (HPA)
activity and impaired stress responsiveness. Previously, we demonstrated that
the HPA response to hypoglycemia is significantly impaired in diabetic ...
Cited by 18 - Related articles - All 5 versions

Molecular and functional resistance to insulin in hypothalamus of rats exposed to cold

- physiology.org
MA Torsoni, JB Carvalheira… - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc
Insulin and leptin act in the hypothalamus, providing robust anorexigenic
signals. The exposure of homeothermic animals to a cold environment leads to
increased feeding, accompanied by sustained low levels of insulin and ...
Cited by 14 - Related articles - BL Direct - All 5 versions

Effects of diabetes and recurrent hypoglycemia on the regulation of the sympathoadrenal …

- physiology.org
KE Inouye, O Chan, JTY Yue, SG Matthews, M … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc
Epinephrine, norepinephrine, and corticosterone responses to hypoglycemia are
impaired in diabetic rats. Recurrent hypoglycemia further diminishes epinephrine
responses. This study examined the sympathoadrenal system and hypothalamo- ...
Cited by 14 - Related articles - All 4 versions

Hyperglycemia does not increase basal hypothalamo-pituitary-adrenal activity in diabetes …

- physiology.org
O Chan, K Inouye, EM Akirav, E Park, MC … - … Journal of Physiology- Regulatory, Integrative and …, 2005 - Am Physiological Soc
Recently, we established that hypothalamo-pituitary-adrenal (HPA) and
counterregulatory responses to insulin-induced hypoglycemia were impaired in
uncontrolled streptozotocin (STZ)-diabetic (65 mg/kg) rats and insulin ...
Cited by 11 - Related articles - BL Direct - All 4 versions

Blockade of GABAA receptors in the ventromedial hypothalamus further stimulates glucagon …

- shouxi.net
O Chan, W Zhu, Y Ding, RJ McCrimmon, RS … - Diabetes, 2006 - Am Diabetes Assoc
Hypoglycemia provokes a multifaceted counterregulatory response involving the
sympathoadrenal system, stimulation of glucagon secretion, and the
hypothalamo-pituitary-adrenal axis that is commonly impaired in diabetes. ...
Cited by 11 - Related articles - BL Direct - All 5 versions


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