H Hyöty, K Taylor - Diabetologia, 2002 - Springer Abstract. Viruses have long been considered a major environmental factor in the aetiology of
Type I (insu- lin-dependent) diabetes mellitus and recent work has greatly confirmed and extended
this role. In addition to the enteroviruses, there are several other viruses which, from time ... Cited by 146 - Related articles - BL Direct - All 3 versions
HS Jun, JW Yoon - Metabolism Research and Reviews, 2002 - dels.nas.edu Type 1 diabetes results from the destruction of pancreatic beta cells. Genetic factors are believed
to be a major com- ponent for the development of type 1diabetes, but the con- cordance rate
for the development of diabetes in identical twins is only about 40%, suggesting that non- ... Cited by 113 - Related articles - View as HTML - BL Direct - All 5 versions
- ►bmjjournals.com MA Kelly, ML Rayner, CH Mijovic, AH Barnett - Molecular Pathology, 2003 - Assoc Clin Pathol Type 1 diabetes is a T cell mediated autoimmune disease, characterised by the selective destruction
of pancreatic ß cells, and susceptibility is determined by a combination of genetic and environmental
factors. The environmental agents implicated include viruses and dietary factors, although ... Cited by 53 - Related articles - BL Direct - All 8 versions
A Rabinovitch, WL Suarez-Pinzon - Reviews in Endocrine & Metabolic …, 2003 - Springer Page 1. Reviews in Endocrine & Metabolic Disorders 2003;4:291–299 C 2003 Kluwer
Academic Publishers. Manufactured in The Netherlands. Role of Cytokines in the
Pathogenesis of Autoimmune Diabetes Mellitus Alex Rabinovitch ... Cited by 47 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org M Flodström, D Tsai, C Fine, A Maday, N Sarvetnick - Diabetes, 2003 - Am Diabetes Assoc Pancreatic β-cell antiviral defense plays a critical role in protection from coxsackievirus B4
(CVB4)-induced diabetes. In the present study, we tested the hypothesis that interferon
(IFN)-induced antiviral defense determines β-cell survival after infection by the human ... Cited by 23 - Related articles - BL Direct - All 4 versions
R Varela-Calvino, M Peakman - Diabetes/Metabolism Reviews - interscience.wiley.com The development of type 1 diabetes mellitus (T1DM) has been linked to exposure to environmental
triggers, with Enteroviruses (EV) historically considered the prime suspects. Early serological
studies suggested a link between EV infections and the development of T1DM and, ... Cited by 20 - Related articles - BL Direct - All 3 versions
H Hyöty - Endocrinology and metabolism clinics of North America, 2004 - Elsevier Viruses are among the most studied potential environmental triggers of type 1 diabetes mellitus
(T1D). Viruses can cause β-cell damage and diabetes in many mammals [1 and 2], and it is logical
to ask whether they could do the same in humans. Although the role of viruses in human ... Cited by 19 - Related articles - BL Direct - All 3 versions
N Lammi, M Karvonen, J Tuomilehto - Medical science monitor: …, 2005 - ncbi.nlm.nih.gov Type 1 diabetes mellitus (T1DM) results from environmental factors acting on genetically susceptible
individuals. Microbial infections and their immunological consequences are suspected to take
part in the pathogenesis of T1DM. Congenital rubella infection has been strongly ... Cited by 19 - Related articles - All 6 versions
P Kulmala - Pediatric Drugs, 2003 - ingentaconnect.com The clinical manifestation of type 1 diabetes mellitus is preceded by an asymptomatic prodromal
period Abstract called prediabetes or preclinical diabetes. It may last from a few months to several
years, during which the autoimmune destruction of the insulin-producing β-cells in the ... Cited by 17 - Related articles - BL Direct - All 3 versions
S Paraskevas, JE Coad, A Gruessner, R … - Transplantation, 2005 - journals.lww.com Skip Navigation Links Home > September 15, 2005 - Volume 80 - Issue 5 > Posttransplant Lymphoproliferative
Disorder in Pancreas Tran... ... 1 Department of Surgery, University of Minnesota,
Minneapolis, MN. ... 2 Department of Pathology, University of Minnesota, Minneapolis, MN. Cited by 14 - Related articles - BL Direct - All 3 versions
