ER Pearson, BJ Starkey, RJ Powell, FM … - The Lancet, 2003 - Elsevier Type 2 diabetes shows evidence of underlying heterogeneity. No studies have
assessed whether different causes for diabetes change the response to oral
hypoglycaemic therapy. In a few cases, patients with diabetes caused by ... Cited by 132 - Related articles - All 4 versions
- ►nih.gov S Xuan, T Kitamura, J Nakae, K Politi, Y Kido, … - Journal of Clinical Investigation, 2002 - Am Soc Clin Investig Defective insulin secretion is a feature of type 2 diabetes that results from
inadequate compensatory increase of β cell mass and impaired glucose-dependent
insulin release. β cell proliferation and secretion are thought to be ... Cited by 115 - Related articles - BL Direct - All 11 versions
- ►cell.com P Akpinar, S Kuwajima, J Krützfeldt, M Stoffel - Cell Metabolism, 2005 - Elsevier The signals and molecular mechanisms that regulate the replication of terminally
differentiated β cells are unknown. Here, we report the identification and
characterization of transmembrane protein 27 (Tmem27, collectrin) in ... Cited by 38 - Related articles - All 12 versions
- ►nih.gov H Thomas, S Senkel, S Erdmann, T Arndt, G … - Nucleic Acids Research, 2004 - Oxford Univ Press Using the rat insulinoma cell line INS-1 we generated ß-cell clones that are
most efficient for gene transfer, as they contain an FRT site for Flp
recombinase-mediated, site-directed integration of a single copy transgene. ... Cited by 26 - Related articles - All 3 versions
- ►diabetesjournals.org H Wang, K Hagenfeldt-Johansson, LA Otten, … - Diabetes, 2002 - Am Diabetes Assoc Six monogenic forms of maturity-onset diabetes of the young (MODY) have been
identified to date. Except for MODY2 (glucokinase), all other MODY subtypes have
been linked to transcription factors. We have established a MODY3 ... Cited by 23 - Related articles - BL Direct - All 3 versions
- ►physiology.org K Robertson, Y Lu, K De Jesus, B Li, Q Su, PK … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Insulin-like growth factor I (IGF-I) is normally produced from hepatocytes and
various other cells and tissues, including the pancreas, and is known to
stimulate islet cell replication in vitro, prevent Fas-mediated β-cell ... Cited by 13 - Related articles - BL Direct - All 3 versions
SG Wilson, G Adam, M Langdown, R Reneland … - European Journal of Human Genetics, 2006 - twinsuk.eu Linkage of obesity-related phenotypes SG Wilson et al Table 1 Morphometric data
for female dizygous twins Initial twin cohort Expanded twin cohort Association
cohort Age (years) Height (m) Weight (kg) Central fat mass (g) BMI (kg/m2) ... Cited by 11 - Related articles - BL Direct - All 9 versions
CR Lockwood, C Bingham, TM Frayling - Molecular Genetics and Metabolism, 2003 - Elsevier HNF1-α is a transcription factor present in β-cells. Mutations in the HNF1-α
gene cause maturity-onset diabetes of the young (MODY), but the exact mechanism
is not known. Several studies have highlighted genes down-regulated in ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►endocrinology-journals.org HJ Welters, S Senkel, L Klein-Hitpass, S … - Journal of Endocrinology, 2006 - Soc Endocrinology Mutations in the gene encoding hepatocyte nuclear factor (HNF)1ß result in
maturity-onset diabetes of the young-(MODY)5, by impairing insulin secretory
responses and, possibly, by reducing ß-cell mass. The functional role of ... Cited by 10 - Related articles - BL Direct - All 3 versions
M Bertolotti, C Gabbi, C Anzivino, M Crestani, … - European journal of clinical investigation, 2007 - interscience.wiley.com Department of Medicine, Endocrinology, Metabolism and Geriatrics, University of
Modena and Reggio Emilia, Modena, Italy (M. Bertolotti, C. Gabbi, C. Anzivino,
D. Macchioni, L. Carulli, M. Ricchi, P. Loria, N. Carulli); Department of ... Cited by 7 - Related articles - BL Direct - All 4 versions
