- ►endojournals.org I Kharroubi, L Ladriere, AK Cardozo, Z … - Endocrinology, 2004 - Endocrine Soc Apoptosis is probably the main form of ß-cell death in both type 1 diabetes
mellitus (T1DM) and T2DM. In T1DM, cytokines contribute to ß-cell destruction
through nuclear factor- B (NF- B) activation. Previous studies suggested ... Cited by 134 - Related articles - BL Direct - All 3 versions
E Szegezdi, U Fitzgerald, A Samali - Ann NY Acad Sci, 2003 - toxicology.usu.edu ABSTRACT: The labyrinth of the endoplasmic reticulum (ER) interweaves the
cytosol and connects to the nucleus, mitochondria, and the plasma membrane. In
the lumen of the ER, the essential function of lipid synthesis, Ca2+ ... Cited by 119 - Related articles - View as HTML - BL Direct - All 7 versions
- ►shouxi.net AK Cardozo, F Ortis, J Storling, YM Feng, J … - Diabetes, 2005 - Am Diabetes Assoc Cytokines and free radicals are mediators of β-cell death in type 1 diabetes.
Under in vitro conditions, interleukin-1β (IL-1β) + γ-interferon (IFN-γ)
induce nitric oxide (NO) production and apoptosis in rodent and human ... Cited by 102 - Related articles - All 8 versions
- ►aacrjournals.org K Zu, C Ip - Cancer research, 2003 - AACR The ongoing Selenium and Vitamin E Chemoprevention Trial is designed to evaluate
the efficacy of these two agents, either individually or in combination, in
reducing the incidence of prostate cancer in healthy men over 55 years of ... Cited by 82 - Related articles - BL Direct - All 4 versions
- ►rupress.org M Kalai, M Lamkanfi, G Denecker, M … - Journal of Cell Biology, 2003 - jcb.rupress.org Phylogenetic analysis clusters caspase-12 with the inflammatory caspases 1 and
11. We analyzed the expression of caspase-12 in mouse embryos, adult organs, and
different cell types and tested the effect of interferons (IFNs) and other ... Cited by 63 - Related articles - BL Direct - All 9 versions
J Groenendyk, M Michalak - ACTA BIOCHIMICA POLONICA-ENGLISH EDITION-, 2005 - actabp.pl The ER is one of the most important folding compartments within the cell, as
well as an intra- cellular Ca2+ storage organelle and it contains a number of
Ca2+ regulated molecular chaperones responsible for the proper folding of ... Cited by 43 - Related articles - View as HTML - BL Direct - All 7 versions
- ►biologists.org DA Cunha, P Hekerman, L Ladriere, A Bazarra- … - Journal of cell science, 2008 - jcs.biologists.org Free fatty acids (FFA) cause apoptosis of pancreatic β-cells and might
contribute to β-cell loss in type 2 diabetes via the induction of endoplasmic
reticulum (ER) stress. We studied here the molecular mechanisms implicated ... Cited by 23 - Related articles - All 5 versions
M Mizobuchi, H Ogata, I Hatamura, F Saji, F … - Biochemical and Biophysical Research …, 2007 - Elsevier Calcimimetic compounds inhibit not only parathyroid hormone (PTH) synthesis and
secretion, but also parathyroid cell proliferation. The aim of this
investigation is to examine the effect of the calcimimetic compound NPS ... Cited by 18 - Related articles - All 3 versions
- ►nrc-cnrc.gc.ca [PDF] J Turk, S Ramanadham - Canadian journal of physiology and pharmacology, 2004 - article.pubs.nrc-cnrc.gc.ca Page 1. REVIEW / SYNTHÈSE The expression and function of a group VIA
calcium-independent phospholipase A 2 (iPLA 2 ) in -cells 1 ... Cited by 13 - Related articles - All 7 versions