Y Dor, J Brown, OI Martinez, DA Melton - Nature, 2004 - molecool.wustl.edu How tissues generate and maintain the correct number of cells is a fundamental
problem in biology. In principle, tissue turnover can occur by the
differentiation of stem cells, as is well documented for blood, skin and ... Cited by 789 - Related articles - View as HTML - BL Direct - All 26 versions
- ►nih.gov A Ianus, GG Holz, ND Theise, MA Hussain - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig Bone marrow harbors cells that have the capacity to differentiate into cells of
nonhematopoietic tissues of neuronal, endothelial, epithelial, and muscular
phenotype. Here we demonstrate that bone marrow–derived cells populate ... Cited by 517 - Related articles - BL Direct - All 8 versions
MY Donath, PA Halban - Diabetologia, 2004 - Springer Increasing evidence indicates that decreased functional beta-cell mass is the
hallmark of both Type 1 and Type 2 diabetes. This underlies the absolute or
relative insu- lin insufficiency in both conditions. In this For Debate, we ... Cited by 123 - Related articles - BL Direct - All 6 versions
- ►physiology.org L Bouwens, I Rooman - Physiological reviews, 2005 - Am Physiological Soc Beta-cell mass regulation represents a critical issue for understanding
diabetes, a disease characterized by a near-absolute (type 1) or relative (type
2) deficiency in the number of pancreatic beta cells. The number of islet ... Cited by 115 - Related articles - BL Direct - All 6 versions
JJ Meier, A Bhushan, AE Butler, RA Rizza, PC … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Type 1 diabetes is widely held to result from an
irreversible loss of insulin-secreting beta cells. However, insulin secretion is
detectable in some peo- ple with long-standing type 1 diabetes, indicating ... Cited by 103 - Related articles - BL Direct - All 5 versions
LB Chen, XB Jiang, L Yang… - World Journal of Gastroenterology, 2004 - wjgnet.com METHODS: Rat MSCs were isolated from Wistar rats and cultured. Passaged MSCs
were induced to differentiate into islet-like cells under following conditions:
pre-induction with L-DMEM including 10 mmol/L nicotinamide+1 mmol/L b- ... Cited by 91 - Related articles - Cached - BL Direct - All 12 versions
- ►neiltheise.com [PDF] MA Hussain, ND Theise - The Lancet, 2004 - Elsevier Curative therapy for diabetes mellitus mainly implies replacement of functional
insulin-producing pancreatic β cells, with pancreas or islet-cell transplants.
However, shortage of donor organs spurs research into alternative means of ... Cited by 81 - Related articles - All 8 versions
- ►nih.gov M Trucco - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig Type 1 diabetes is the result of an autoimmune attack against the
insulin-producing β cells of the endocrine pancreas. Current treatment for
patients with type 1 diabetes typically involves a rigorous and invasive ... Cited by 69 - Related articles - All 9 versions
M Paris, C Bernard-Kargar, MF Berthault, L … - Endocrinology, 2003 - Endocrine Soc We investigated the specific and associated effects of insulin and glucose on
ß-cell growth and function in adult rats. By combining simultaneous infusion
either of glucose and/or insulin or glucose and diazoxide, three groups of ... Cited by 63 - Related articles - BL Direct - All 6 versions
L Rosenberg, M Lipsett, JW Yoon, M Prentki, R … - Annals of surgery, 2004 - pubmedcentral.nih.gov From the *Department of Surgery, McGill University, Montreal, Quebec, Canada;
†Julia Macfarlane Diabetes Research Center, University of Calgary, Calgary,
Alberta, Canada; the ‡Departments of Nutrition and Biochemistry, ... Cited by 58 - Related articles - BL Direct - All 4 versions
