T Tsuboi, HT McMahon, GA Rutter - Journal of Biological Chemistry, 2004 - ASBMB The molecular mechanisms underlying "kiss and run" or "cavicapture" exocytosis of dense core
secretory vesicles are presently unclear. Although dynamin-1 has previously been implicated
in the recapture process in neurons, the recruitment of this fission protein to a single ... Cited by 65 - Related articles - BL Direct - All 9 versions
AL Notkins - Journal of Biological Chemistry, 2002 - ASBMB Insulin release and action. Glucose enters beta cells via the glucose transporter (GLUT2) and
ATP is generated by glycolysis. This results in closure of ATP-sensitive K + channels, depolarization
of the plasma membrane, and opening of voltage-dependent Ca 2+ channels. The influx ... Cited by 58 - Related articles - BL Direct - All 5 versions
- ►rupress.org M Trajkovski, H Mziaut, A Altkruger, J Ouwendijk, … - Journal of Cell …, 2004 - jcb.rupress.org Islet cell autoantigen 512 (ICA512)/IA-2 is a receptor tyrosine phosphatase-like protein associated
with the insulin secretory granules (SGs) of pancreatic ß-cells. Here, we show that exocytosis
of SGs and insertion of ICA512 in the plasma membrane promotes the Ca 2+ -dependent ... Cited by 35 - Related articles - All 11 versions
- ►nih.gov S Harashima, A Clark, MR Christie, AL … - Proceedings of the …, 2005 - National Acad Sciences IA-2 is an enzymatically inactive member of the transmembrane protein tyrosine phosphate family
located in dense core secretory vesicles and a major autoantigen in type 1 diabetes. Recent
studies showed that targeted disruption of the IA-2 gene in mice resulted in impairment of ... Cited by 27 - Related articles - All 9 versions
A Kubosaki, S Gross, J Miura, K Saeki, M Zhu, S … - Diabetes, 2004 - Am Diabetes Assoc Insulinoma-associated protein (IA)-2β, also known as phogrin, is an enzymatically inactive member
of the transmembrane protein tyrosine phosphatase family and is located in dense-core secretory
vesicles. In patients with type 1 diabetes, autoantibodies to IA-2β appear years before the ... Cited by 26 - Related articles - BL Direct - All 8 versions
HE Larsson, K Lynch, B Lernmark, A Nilsson, G … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: The aim of our study was to test the hypothesis that HLA genotypes
conferring risk of diabetes, cord blood autoantibodies, or both are associated with increased
birthweight. Methods: HLA genotypes were determined in dried blood spots of cord blood ... Cited by 27 - Related articles - BL Direct - All 3 versions
- ►cjb.net T Cai, T Fukushige, AL Notkins, M Krause - Journal of Neuroscience, 2004 - neuro.cjb.net IA-2 (insulinoma-associated protein 2), a major autoantigen in type 1 diabetes, is a
receptor-tyrosine phosphatase-like protein associated with the membrane of secretory granules
of neural and endocrine-specific cells. Loss of IA-2 activity in the mouse results in ... Cited by 20 - Related articles - BL Direct - All 7 versions
- ►pnas.org A Doi, T Shono, M Nishi, H Furuta, H … - Proceedings of the …, 2006 - National Acad Sciences Ghrelin is a newly discovered peptide and an endogenous ligand for growth hormone (GH) secretagogue
(GHS) receptor. It has been shown to possess various central and peripheral effects, including
GH secretion, food intake, and gastric and cardiac effects. Ghrelin and the GHS receptor ... Cited by 17 - Related articles - BL Direct - All 5 versions
- ►cam.ac.uk [PDF] B Borgonovo, J Ouwendijk, M Solimena - Current opinion in cell biology, 2006 - Elsevier Since their discovery by electron microscopy more than fifty years ago, secretory granules
(SGs, also known as large dense core vesicles) of neuroendocrine cells have attracted the attention
of cell biologists. This is because they are the predominant neuroendocrine organelles, ... Cited by 17 - Related articles - All 5 versions
