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Scholar Results 1 - 10 of about 99 citing Xu: Altered tumor necrosis factor-α (TNF-α) processing in adipocytes and increased expression.... (0.08 sec) 

Insulin resistance and chronic cardiovascular inflammatory syndrome

- endojournals.org
JM Fernandez-Real, W Ricart - Endocrine Reviews, 2003 - Endocrine Soc
Insulin resistance is increasingly recognized as a chronic, low-level,
inflammatory state. Hyperinsulinemia and insulin action were initially proposed
as the common preceding factors of hypertension, low high-density ...
Cited by 429 - Related articles - BL Direct - All 5 versions

Adipose tissue, inflammation, and cardiovascular disease

- ahajournals.org
AH Berg, PE Scherer - Circulation Research, 2005 - Am Heart Assoc
Mounting evidence highlights the role of adipose tissue in the development of a
systemic inflammatory state that contributes to obesity-associated vasculopathy
and cardiovascular risk. Circulating mediators of inflammation participate ...
Cited by 422 - Related articles - All 10 versions

Regulation of adipocytokines and insulin resistance


M Fasshauer, R Paschke - Diabetologia, 2003 - Springer
It has long been known that obesity and insulin resis- tance are linked.
Recently, it has been shown that adi- pocytes secrete several proteins including
tumour ne- crosis factor-α, interleukin-6, resistin, and adiponec- tin. ...
Cited by 285 - Related articles - BL Direct - All 4 versions

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and …

- jbc.org
V Rotter, I Nagaev, U Smith - Journal of Biological Chemistry, 2003 - ASBMB
Several studies have shown a relationship between interleukin (IL) 6 levels and
insulin resistance. We here show that human subcutaneous adipose cells, like
3T3-L1 cells, are target cells for IL-6. To examine putative mechanisms and ...
Cited by 273 - Related articles - BL Direct - All 5 versions

JNK and tumor necrosis factor-α mediate free fatty acid-induced insulin resistance in 3T3-L1 …


MT Nguyen, H Satoh, S Favelyukis, JL … - Journal of Biological Chemistry, 2005 - ASBMB
Lipid infusion and high fat feeding are established causes of systemic and
adipose tissue insulin resistance. In this study, we treated 3T3-L1 adipocytes
with a mixture of free fatty acids (FFAs) to investigate the molecular ...
Cited by 150 - Related articles - BL Direct - All 6 versions

Fat as an endocrine organ: relationship to the metabolic syndrome

- nursing2008.com
L Hutley, JB Prins - The American journal of the medical sciences, 2005 - journals.lww.com
ABSTRACT: Obesity and the metabolic syndrome have both reached pandemic
proportions. Together they have the potential to impact on the incidence and
severity of cardiovascular pathologies, with grave implications for ...
Cited by 116 - Related articles - All 6 versions

Do regional differences in adipocyte biology provide new pathophysiological insights?

- cell.com
M Lafontan, M Berlan - Trends in pharmacological sciences, 2003 - Elsevier
Obesity is an increasing health problem in many countries. Striking differences
exist in the magnitude of the impact of different obesities on comorbidities.
Individuals with peripheral obesity ('pears') possess fat distributed ...
Cited by 108 - Related articles - All 7 versions

The role of TNF-α in insulin resistance


SE Borst - Endocrine, 2004 - Springer
Received January 12, 2004; Revised January 27, 2004; Accepted February 11, 2004.
Author to whom all correspondence and reprint requests should be addressed:
Stephen Borst, Ph.D., VA Medical Center, GRECC – 182, 1601 SW Archer Rd., ...
Cited by 105 - Related articles - BL Direct - All 2 versions

Nonalcoholic fatty liver disease: cytokine-adipokine interplay and regulation of insulin …


H Tilg, GS Hotamisligil - Gastroenterology, 2006 - Elsevier
Nonalcoholic fatty liver disease (NAFLD), the major reason for abnormal liver
function in the Western world, is associated with obesity and diabetes and is
characterized by insulin resistance (IR). IR is regulated by mediators ...
Cited by 95 - Related articles - All 17 versions

Associations of body fat and its changes over time with quality of life and prospective …

- ajcn.org
K Kalantar-Zadeh, N Kuwae, DY Wu, RS … - American Journal of Clinical Nutrition, 2006 - Am Soc Nutrition
2 Supported by a National Institutes of Health, National Institute of Diabetes,
Digestive and Kidney Disease grant no. DK61162 (to KK-Z), a research grant from
Amgen, Inc, (to KK-Z and JDK), a research grant from DaVita, Inc (to KK-Z), ...
Cited by 83 - Related articles - BL Direct - All 7 versions


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