H Yki-Jarvinen - New England Journal of Medicine, 2004 - content.nejm.org Insulin resistance both precedes and predicts type 2 diabetes mellitus. 1 Although exercise and
weight loss ameliorate insulin resistance and may in some cases prevent or delay onset of the
disease, 2 therapy that combats insulin resistance in those who fail to change their ... Cited by 847 - Related articles - BL Direct - All 6 versions
G Bedogni, L Miglioli, F Masutti, C Tiribelli, G … - Hepatology, 2005 - giorgiobedogni.it The prevalence of and the risk factors for fatty liver have not undergone a formal evaluation in
a representative sample of the general population. We therefore performed a cross- sectional
study in the town of Campogalliano (Modena, Italy), within the context of the Dionysos ... Cited by 207 - Related articles - View as HTML - BL Direct - All 5 versions
E Bugianesi, AJ McCullough, G Marchesini… - Hepatology, 2005 - interscience.wiley.com Insulin resistance (IR) is the pathophysiological hallmark of nonalcoholic fatty liver disease
(NAFLD), one of the most common causes of chronic liver disease in Western countries. We
review the definition of IR, the methods for the quantitative assessment of insulin action, ... Cited by 170 - Related articles - BL Direct - All 3 versions
H Yki-Järvinen - Annals of Medicine, 2005 - informahealthcare.com Insulin resistance in humans is not always accompanied by obesity, since severe insulin resistance
also characterizes patients lacking subcutaneous fat such as those with HAART‐ (highly‐active
antiretroviral therapy)‐associated lipodystrophy. Both obese and lipodystrophic patients, ... Cited by 145 - Related articles - BL Direct - All 10 versions
J Westerbacka, A Corner, M Tiikkainen, M Tamminen, … - Diabetologia, 2004 - Springer Aims/hypothesis. Fat accumulation in the liver has been shown to be closely correlated with hepatic
insu- lin resistance and features of insulin resistance, also independently of body weight. It remains
to be estab- lished how fat in the liver correlates with that in other depots, and whether ... Cited by 120 - Related articles - BL Direct - All 7 versions
- ►endojournals.org KM Utzschneider, SE Kahn - Journal of Clinical Endocrinology & …, 2006 - Endocrine Soc Evidence Synthesis: Insulin resistance in NAFLD is characterized by reductions in
whole-body, hepatic, and adipose tissue insulin sensitivity. The mechanisms underlying the accumulation
of fat in the liver may include excess dietary fat, increased delivery of free fatty acids to the ... Cited by 116 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org AJG Hanley, K Williams, A Festa, LE Wagenknecht, RB … - Diabetes, 2005 - Am Diabetes Assoc Nonalcoholic fatty liver disease (NAFLD) is emerging as a component of the metabolic
syndrome, although it is not known whether markers of NAFLD, including elevated concentrations
of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline ... Cited by 117 - Related articles - BL Direct - All 6 versions
M Adiels, MR Taskinen, C Packard, MJ Caslake, A … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 755–765 DOI 10.1007/s00125-005-0125-z ARTICLE M.
Adiels . M.-R. Taskinen . C. Packard . MJ Caslake . A. Soro-Paavonen . J. Westerbacka . S.
Vehkavaara . A. Häkkinen . S.-O. Olofsson . H. Yki-Järvinen . J. Borén ... Cited by 116 - Related articles - BL Direct - All 5 versions
N Sattar, O Scherbakova, I Ford, DSJ O'Reilly, A … - Diabetes, 2004 - Am Diabetes Assoc We examined the association of serum alanine aminotransferase (ALT) with features of the metabolic
syndrome and whether it predicted incident diabetes independently of routinely measured factors
in 5,974 men in the West of Scotland Coronary Prevention Study. A total of 139 men ... Cited by 111 - Related articles - BL Direct - All 10 versions
AJG Hanley, K Williams, A Festa, LE Wagenknecht, RB … - Diabetes, 2004 - Am Diabetes Assoc A limited number of studies have reported associations of markers of liver injury, including elevated
concentrations of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), with
prospective risk of type 2 diabetes. However, only one study has adjusted for a detailed ... Cited by 107 - Related articles - BL Direct - All 9 versions