C De Alvaro, T Teruel, R Hernandez, M … - Journal of Biological Chemistry, 2004 - ASBMB Insulin stimulation produced a reliable 3-fold increase in glucose uptake in
primary neonatal rat myotubes, which was accompanied by a similar effect on
GLUT4 translocation to plasma membrane. Tumor necrosis factor (TNF)-α ... Cited by 142 - Related articles - BL Direct - All 4 versions
- ►physiology.org I Talior, M Yarkoni, N Bashan, H Eldar- … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc Increased oxidative stress is believed to be one of the mechanisms responsible
for hyperglycemia-induced tissue damage and diabetic complications. In these
studies, we undertook to characterize glucose uptake and oxidative stress ... Cited by 47 - Related articles - BL Direct - All 3 versions
EP Araujo, CT De Souza, AL Gasparetti, M … - Endocrinology, 2005 - Endocrine Soc Insulin receptor substrate-1 (IRS-1) has an important role as an early
intermediary between the insulin and IGF receptors and downstream molecules that
participate in insulin and IGF-I signal transduction. Here we employed an ... Cited by 31 - Related articles - All 5 versions
- ►nih.gov SR Sampson, DR Cooper - Molecular genetics and metabolism, 2006 - Elsevier Recent studies implicate specific PKC isoforms in the insulin-signaling cascade.
Insulin activates PKCs α, βII, δ and ζ in several cell types. In addition,
as will be documented in this review, certain members of the PKC family may ... Cited by 24 - Related articles - All 4 versions
T Rosenzweig, S Aga-Mizrachi, A Bak, SR … - Cellular signalling, 2004 - Elsevier Insulin stimulation of skeletal muscle results in rapid activation of protein
kinase Cδ (PKCδ), which is associated with its tyrosine phosphorylation and
physical association with insulin receptor (IR). The mechanisms underlying ... Cited by 21 - Related articles - All 3 versions
- ►diabetesjournals.org I Nieto-Vazquez, S Fernández-Veledo, C de … - Diabetes, 2007 - Am Diabetes Assoc Protein–tyrosine phosphatase (PTP)1B is a negative regulator of insulin
signaling and a therapeutic target for type 2 diabetes. In this study, we have
assessed the role of PTP1B in the insulin sensitivity of skeletal muscle ... Cited by 21 - Related articles - BL Direct - All 6 versions
C de Alvaro, T Teruel, R Hernandez, M … - J Biol Chem, 2004 - ASBMB Insulin stimulation produced a reliable 3-fold in- crease in glucose uptake in
primary neonatal rat myo- tubes, which was accompanied by a similar effect on
GLUT4 translocation to plasma membrane. Tumor ne- crosis factor (TNF)- ... Cited by 20 - Related articles
- ►endojournals.org R Nawaratne, A Gray, CH Jorgensen, CP … - Molecular Endocrinology, 2006 - Endocrine Soc Phosphorylation of insulin receptor substrate (IRS) proteins on serine residues
is an important posttranslational modification that is linked to insulin
resistance. Several phosphoserine sites on IRS1 have been identified; the ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►endojournals.org N Ghosh, N Patel, K Jiang, JE Watson, J … - Endocrinology, 2007 - Endocrine Soc Elevated TNF levels are associated with insulin resistance, but the molecular
mechanisms linking cytokine signaling to impaired insulin function remain
elusive. We previously demonstrated a role for Akt in insulin regulation of ... Cited by 12 - Related articles - BL Direct - All 4 versions
- ►animal-science.org M Lorenzo, S Fernandez-Veledo, R Vila- … - Journal of animal Science, 2008 - animal-science.org Insulin resistance is an important contributor to the pathogenesis of type 2
diabetes, and obesity is a risk factor for its development, in part because
adipose tissue secretes proteins, called adipokines, that may influence ... Cited by 8 - Related articles - All 5 versions
