- ►endojournals.org ZY Fang, JB Prins, TH Marwick - Endocrine reviews, 2004 - Endocrine Soc The existence of a diabetic cardiomyopathy is supported by epidemiological findings showing
the association of diabetes with heart failure; clinical studies confirming the association of diabetes
with left ventricular dysfunction independent of hypertension, coronary artery disease, ... Cited by 233 - Related articles - BL Direct - All 8 versions
- ►critcaremed.com V Srinivasan, PC Spinella, HR Drott, CL Roth, … - Pediatric Critical Care …, 2004 - journals.lww.com Clinical Fellow, Pediatric Critical Care Medicine, The Children's Hospital of Philadelphia, Division
of Critical Care Medicine, Philadelphia, PA (VS); Assistant Professor, Department of
Pediatrics, Uniformed Services University of Health Sciences, San Antonio, TX (PCS); ... Cited by 168 - Related articles - All 6 versions
S Boudina, ED Abel - Circulation, 2007 - Am Heart Assoc The prevalence of diabetes mellitus is growing rapidly. It is estimated that globally the number
of adults affected with diabetes will increase from 135 million in 1995 to 300 million by 2025.
1 Patients with diabetes mellitus are at increased risk for cardiovascular diseases. Thus, ... Cited by 140 - Related articles - All 5 versions
UN Das - Critical Care, 2002 - biomedcentral.com Stress hyperglycemia and diabetes mellitus with myocardial infarction are associated with increased
risk for in-hospital mortality, congestive heart failure, or cardiogenic shock. Hyperglycemia triggers
free radical generation and suppresses endothelial nitric oxide generation, and thus ... Cited by 127 - Related articles - Cached - BL Direct - All 15 versions
T Mandrup-Poulsen - Biochemical pharmacology, 2003 - Elsevier Failure of insulin producing pancreatic β-cells is a common characteristic of type 1
(insulin-dependent) and type 2 (insulin non-dependent) diabetes mellitus. Accumulating evidence
suggests that programmed cell death (apoptosis) is the main form of β-cell death in these ... Cited by 71 - Related articles - All 5 versions
D An, B Rodrigues - American Journal of Physiology- Heart and …, 2006 - Am Physiological Soc In patients with diabetes, an increased risk of symptomatic heart failure usually develops in the
presence of hypertension or ischemic heart disease. However, a predisposition to heart failure
might also reflect the effects of underlying abnormalities in diastolic function that can ... Cited by 67 - Related articles - BL Direct - All 5 versions
L Cai, J Wang, Y Li, X Sun, L Wang, Z Zhou, YJ Kang - Diabetes, 2005 - Am Diabetes Assoc The mechanisms of metallothionein prevention of diabetic cardiomyopathy are largely
unknown. The present study was performed to test whether inhibition of nitrosative damage is
involved in metallothionein prevention of diabetic cardiomyopathy. Cardiac-specific ... Cited by 61 - Related articles - All 5 versions
- ►iovs.org RA Kowluru, SN Abbas - Investigative ophthalmology & visual science, 2003 - ARVO METHODS. Mitochondria and cytosol fractions were prepared from retina of rats with
streptozotocin-induced diabetes and from the isolated retinal endothelial cells and pericytes
incubated in 5 or 20 mM glucose medium for up to 10 days in the presence of superoxide ... Cited by 52 - Related articles - BL Direct - All 4 versions
DM Niedowicz, DL Daleke - Cell biochemistry and biophysics, 2005 - Springer The morbidity and mortality associated with diabetes is the result of the myriad complications
related to the disease. One of the most explored hypotheses to explain the onset of complications
is a hyperglycemia-induced increase in oxidative stress. Reactive oxygen species (ROS) ... Cited by 53 - Related articles - BL Direct - All 6 versions
- ►onlinejacc.org L Cai, Y Wang, G Zhou, T Chen, Y Song, X Li, YJ … - Journal of the American …, 2006 - Elsevier Our previous study showed that cardiac apoptosis as a major early cellular response to diabetes
is induced by hyperglycemia-derived oxidative stress that activates a mitochondrial cytochrome
c-mediated caspase-3 activation pathway. Metallothionein (MT) as a potent antioxidant ... Cited by 51 - Related articles - BL Direct - All 20 versions
