- ►mpg.de [PDF] R Branson, N Potoczna, JG Kral, KU Lentes, … - New England Journal …, 2003 - content.nejm.org Methods We sequenced the complete MC4R coding region, the region of the proopiomelanocortin
gene (POMC) encoding the melanocyte-stimulating hormone, and the leptin-binding domain
of LEPR in 469 severely obese white subjects (370 women and 99 men; mean [±SE] age, ... Cited by 192 - Related articles - BL Direct - All 10 versions
H Ge, L Huang, T Pourbahrami, C Li - Journal of Biological Chemistry, 2002 - ASBMB Leptin is an adipocyte-derived hormone with potent effects on food intake and body weight. Genetically
obese rodents with mutations of leptin or leptin receptor develop morbid obesity and
diabetes. The receptor for leptin, OB-R, is alternatively spliced to at least five transcripts, ... Cited by 84 - Related articles - BL Direct - All 4 versions
- ►endojournals.org G Yang, H Ge, A Boucher, X Yu, C Li - Molecular Endocrinology, 2004 - Endocrine Soc Soluble leptin receptor (SLR) represents the major leptin binding activity in plasma. It is generated
by alternative splicing of OB-R mRNA (OB-Re) and/or ectodomain shedding of membrane-spanning
receptors. To determine the role of SLR in leptin activation of its long-form receptor, ... Cited by 66 - Related articles - BL Direct - All 4 versions
J Pařízková, AP Hills - 2005 - books.google.com Second Edition CHILDHOOD OBESITY Prevention and Treatment Jana Parizkova Andrew Hills
CRC PRESS ... CHILDHOOD OBESITY Prevention And Treatment Second Edition Thi 6 One
7TXS-LFT-ADRD ... CHILDHOOD OBESITY Prevention And Treatment Second Edition ... Cited by 37 - Related articles - All 5 versions
T Ogawa, H Hirose, Y Yamamoto, K Nishikai, K … - Metabolism, 2004 - Elsevier Leptin plays an important role in the regulation of body weight and is known to circulate in both
free and bound forms. One of the leptin receptor isoforms exists in a circulating soluble form that
can bind leptin. Clinical studies have shown that soluble leptin receptor (sOB-R) levels ... Cited by 25 - Related articles - All 10 versions
SE Cohen, E Kokkotou, SB Biddinger, T Kondo, R … - Journal of Biological …, 2007 - ASBMB Liver-specific insulin receptor knock-out (LIRKO) mice display hyperinsulinemia, abnormal glucose
metabolism, and progressive liver dysfunction. In addition, circulating leptin levels appear to
be increased more than 10-fold. However, food intake, body weight, and adipose mass ... Cited by 18 - Related articles - All 5 versions
AA Venner, ME Lyon, PK Doyle-Baker - Clinical biochemistry, 2006 - Elsevier Leptin, a hormone made by adipocytes, is an important circulating signal for the regulation of
body weight. A review of the scientific literature (PubMed Search 1994 to 2005) for studies examining
the relationship among leptin, pediatric obesity and the impact of exercise intervention ... Cited by 13 - Related articles - All 3 versions
- ►oxfordjournals.org N Kado, J Kitawaki, H Koshiba, H Ishihara, Y Kitaoka, … - Human Reproduction, 2003 - ESHRE BACKGROUND: The aim of this study was to investigate the relationships between the serum
levels of soluble leptin receptor (SLEPR), and total, free and bound leptin, and the change in
the serum SLEPR level during an IVF cycle. METHODS: Serum concentrations of leptin ... Cited by 12 - Related articles - BL Direct - All 5 versions
N Buyan, O Özkaya, A Bideci, O Söylemezoğlu, P … - Pediatric Nephrology, 2003 - Springer Abstract Leptin may contribute to renal pathology in some situations by stimulating transforming
growth fac- tor-β1 (TGF-β1) synthesis. The soluble leptin receptor (sOb-R) is a transport protein
contributing to binding and activation of circulating leptin. We investigated the interaction ... Cited by 11 - Related articles - BL Direct - All 3 versions
- ►endojournals.org N Gallardo, C Arribas, M Villar, M Ros, JM Carrascosa, … - Endocrinology, 2005 - Endocrine Soc In rodents, soluble leptin receptor (SLR) may be generated by alternative splicing of ObR mRNA
and/or as a cleavage product of ObR membrane-anchored receptors. In this study, we investigated
the contribution of both processes on the generation of SLR in 3-, 8-, and 24-month-old ... Cited by 10 - Related articles - BL Direct - All 7 versions
