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Scholar Results 1 - 10 of about 57 citing Marion: The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2.... (0.13 sec) 

ARED 2.0: an update of AU-rich element mRNA database

- nih.gov
T Bakheet, BRG Williams, KSA Khabar - Nucleic acids research, 2003 - Oxford Univ Press
The Adenylate Uridylate (AU)-Rich Element Database, ARED-mRNA version 2.0,
contains information not present in the previous ARED. This includes additional
data entries, new information and links to Unigene, LocusLink, RefSeq ...
Cited by 93 - Related articles - BL Direct - All 12 versions

Phosphoinositide signaling disorders in human diseases


C Pendaries, H Tronchère, M Plantavid, B … - FEBS letters, 2003 - Elsevier
Phosphoinositides (PIs) play an essential role in diverse cellular functions.
Their intracellular level is strictly regulated by specific PI kinases,
phosphatases and phospholipases. Recent discoveries indicate that ...
Cited by 80 - Related articles - All 6 versions

Programmed disorders of-cell development and function as one cause for type 2 diabetes? …


B Portha - Diabetes/Metabolism Reviews - interscience.wiley.com
Now that the reduction in -mass has been clearly established in humans with type
2 diabetes mellitus (T2DM) [1-4], the debate focuses on the possible mechanisms
responsible for decreased -cell number and impaired -cell function and ...
Cited by 50 - Related articles - BL Direct - All 4 versions

The human and mouse complement of SH2 domain proteins—establishing the boundaries of …

- cell.com
BA Liu, K Jablonowski, M Raina, M Arcé, T … - Molecular Cell, 2006 - Elsevier
SH2 domains are interaction modules uniquely dedicated to the recognition of
phosphotyrosine sites and are embedded in proteins that couple protein-tyrosine
kinases to intracellular signaling pathways. Here, we report a ...
Cited by 47 - Related articles - All 20 versions

SH 2-containing Inositol Phosphatase 2 Predominantly Regulates Akt 2, and Not Akt 1, …


T Sasaoka, T Wada, K Fukui, S Murakami, H … - Journal of Biological Chemistry, 2004 - ASBMB
SH2-containing inositol phosphatase 2 (SHIP2) is a physiologically important
negative regulator of insulin signaling by hydrolyzing the phosphatidylinositol
(PI) 3-kinase product PI 3,4,5-trisphosphate in the target tissues of ...
Cited by 41 - Related articles - BL Direct - All 4 versions

[CITATION] The termination of PI3K signalling by SHIP1 and SHIP2 inositol 5-phosphatases.


K Backers, D Blero, N Paternotte, J Zhang, C … - Advances in enzyme regulation, 2003 - ncbi.nlm.nih.gov
1: Adv Enzyme Regul. 2003;43:15-28. The termination of PI3K signalling by
SHIP1 and SHIP2 inositol 5-phosphatases. Backers K, Blero ...
Cited by 41 - Related articles - All 3 versions

Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with …

- pnas.org
PY Woon, PJ Kaisaki, J Bragança, MT … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
Many aspects of physiology and behavior follow a circadian rhythm. Brain and
muscle Arnt-like protein-1 (BMAL1) is a key component of the mammalian molecular
clock, which controls circadian oscillations. In the rat, the gene encoding ...
Cited by 29 - Related articles - BL Direct - All 8 versions

Obesity and diabetes gene discovery approaches


K Walder, D Segal, J Jowett, J Blangero, GR … - Current pharmaceutical design, 2003 - ingentaconnect.com
Abstract: New treatments are currently required for the common metabolic
diseases obesity and type 2 diabetes. The identification of physiological and
biochemical factors that underlie the metabolic disturbances observed in ...
Cited by 23 - Related articles - BL Direct - All 4 versions

SH 2-containing 5'-Inositol Phosphatase, SHIP 2, Regulates Cytoskeleton Organization …


NK Prasad, SJ Decker - Journal of Biological Chemistry, 2005 - ASBMB
Phosphoinositide lipid second messengers are integral components of signaling
pathways mediated by insulin, growth factors, and integrins. SHIP2
dephosphorylates phosphatidylinositol 3,4,5-trisphosphate generated by the ...
Cited by 23 - Related articles - All 5 versions

Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5′-phosphatase 2 …

- shouxi.net
K Fukui, T Wada, S Kagawa, K Nagira, M … - Diabetes, 2005 - Am Diabetes Assoc
We investigated the role of hepatic SH2-containing inositol 5′-phosphatase 2
(SHIP2) in glucose metabolism in mice. Adenoviral vectors encoding wild-type
SHIP2 (WT-SHIP2) and a dominant-negative SHIP2 (ΔIP-SHIP2) were injected ...
Cited by 24 - Related articles - All 5 versions


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