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Scholar Results 1 - 10 of about 114 citing van Harmelen: Increased lipolysis and decreased leptin production by human omental as compared.... (0.08 sec) 

Intra-abdominal fat is a major determinant of the National Cholesterol Education Program …


DB Carr, KM Utzschneider, RL Hull, K Kodama … - Diabetes, 2004 - Am Diabetes Assoc
The underlying pathophysiology of the metabolic syndrome is the subject of
debate, with both insulin resistance and obesity considered as important
factors. We evaluated the differential effects of insulin resistance and ...
Cited by 346 - Related articles - BL Direct - All 5 versions

PPARγ and human metabolic disease

- nih.gov
RK Semple, VKK Chatterjee, SO'Rahilly - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig
The nuclear receptor family of PPARs was named for the ability of the original
member to induce hepatic peroxisome proliferation in mice in response to
xenobiotic stimuli. However, studies on the action and structure of the 3 ...
Cited by 237 - Related articles - BL Direct - All 10 versions

The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones

- cell.com
P Arner - Trends in Endocrinology & Metabolism, 2003 - Elsevier
Globally, the prevalence of obesity is escalating, and insulin resistance
resulting from increased (predominantly visceral) adipose tissue mass has been
identified as a key factor that could drive parallel rises in type 2 ...
Cited by 234 - Related articles - All 11 versions

Do regional differences in adipocyte biology provide new pathophysiological insights?

- cell.com
M Lafontan, M Berlan - Trends in pharmacological sciences, 2003 - Elsevier
Obesity is an increasing health problem in many countries. Striking differences
exist in the magnitude of the impact of different obesities on comorbidities.
Individuals with peripheral obesity ('pears') possess fat distributed ...
Cited by 109 - Related articles - All 7 versions

Functional studies of mesenchymal stem cells derived from adult human adipose tissue


A Dicker, K Le Blanc, G Åström, V van … - Experimental cell research, 2005 - Elsevier
Recent evidence suggests that cells with the properties of human mesenchymal
stem cells (hMSCs) can be derived from adult peripheral tissues, including
adipose tissue, muscle and dermis. We isolated hMSCs from the ...
Cited by 98 - Related articles - All 3 versions

Hormone-sensitive lipase--new roles for an old enzyme.


SJ Yeaman - Biochemical Journal, 2004 - pubmedcentral.nih.gov
Although described initially as an intracellular adipocyte-specific
triacylglycerol lipase, it is now clear that HSL (hormone-sensitive lipase) is
expressed in multiple tissues and plays a number of roles in lipid ...
Cited by 97 - Related articles - BL Direct - All 8 versions

Human fat cell lipolysis: biochemistry, regulation and clinical role

- ufsc.br [PDF] 
P Arner - Best Practice & Research Clinical Endocrinology & …, 2005 - Elsevier
Release of fatty acids (FAs) from adipose tissue through lipolysis in fat cells
is a key event in many processes. FAs are not only energy substrates but also
signalling molecules and substrates for lipoprotein production by the ...
Cited by 91 - Related articles - All 12 versions

What aspects of body fat are particularly hazardous and how do we measure them?


MB Snijder, RM Van Dam, M Visser, JC … - International journal of epidemiology, 2006 - IEA
Since the 1950s it has been recognized that apart from overall obesity the
distribution of body fat can influence disease risk. 5 In particular an
abdominal fat distribution is associated with metabolic disturbances and ...
Cited by 89 - Related articles - BL Direct - All 8 versions

Trunk fat and leg fat have independent and opposite associations with fasting and postload …

- diabetesjournals.org
MB Snijder, JM Dekker, M Visser, LM Bouter, … - Diabetes Care, 2004 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—In 623 participants of the third examination of
the Hoorn Study, whole-body dual-energy X-ray absorptiometry was performed to
determine fat and lean soft-tissue mass in the trunk and legs. Fasting and ...
Cited by 89 - Related articles - BL Direct - All 5 versions

Functional characterization of human mesenchymal stem cell-derived adipocytes


M Rydén, A Dicker, C Götherström, G … - Biochemical and biophysical research communications, 2003 - Elsevier
The function of adipocytes derived from human mesenchymal stem cells (hMSC) was
investigated for the first time in hMSC from fetal liver (FL) and adult bone
marrow (BM) and compared with preadipocytes from human subcutaneous adipose ...
Cited by 81 - Related articles - All 5 versions


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