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Scholar Results 1 - 10 of 10 citing Ahima: Appetite suppression and weight reduction by a centrally active aminosterol. (0.12 sec) 

Adiponectin acts in the brain to decrease body weight


Y Qi, N Takahashi, SM Hileman, HR Patel, AH … - Nature …, 2004 - members.medscape.com
Adiponectin (ADP) is an adipocyte hormone involved in glucose and lipid metabolism. We detected a
rise in ADP in cerebrospinal fluid after intravenous (iv) injection, consistent with brain
transport. In contrast to leptin, ...
Cited by 268 - Related articles - BL Direct - All 14 versions

[PDF] Natural products to drugs: natural product derived compounds in clinical trials


MS Butler - Natural product reports, 2005 - rsc.org
Natural product and natural product-derived compounds that are being evaluated in clinical trials or
in registration (current 31 December 2004) have been reviewed. Natural product derived drugs
launched in the United States of ...
Cited by 144 - Related articles - BL Direct - All 14 versions

A novel aminosterol reverses diabetes and fatty liver disease in obese mice

- genaera.com [PDF] 
N Takahashi, Y Qi, HR Patel, RS Ahima - Journal of hepatology, 2004 - Elsevier
1436 decreased body weight, specifically fat content, by inhibiting food intake and increasing
energy expenditure. In contrast to weight loss from food restriction, this aminosterol specifically
lowered circulating lipids, ...
Cited by 16 - Related articles - All 7 versions

Squalamine: An Appropriate Strategy against the Emergence of Multidrug …


C Salmi, C Loncle, N Vidal, Y Letourneux, J Fantini, … - PLoS ONE, 2008 - pubmedcentral.nih.gov
We reported that squalamine is a membrane-active molecule that targets the membrane integrity as
demonstrated by the ATP release and dye entry. In this context, its activity may depend on the
membrane lipid composition. This ...
Cited by 3 - Related articles - All 7 versions

Apparent receptor-mediated activation of Ca2+-dependent conductive Cl-transport …

- physiology.org
MN Chernova, DH Vandorpe, JS Clark, JI … - American Journal of …, 2005 - Am Physiological Soc
The shark liver antimicrobial polyaminosterol squalamine is an angiogenesis inhibitor under clinical
investigation as an anti-cancer agent and as a treatment for the choroidal neovascularization
associated with macular ...
Cited by 2 - Related articles - BL Direct - All 5 versions

Recent advances in the discovery and development of PTP-1B inhibitors


S Tam, E Saiah - Drugs of the Future, 2008 - journals.prous.com
Protein-tyrosine phosphatases (PTPs) play crucial roles in intracellular signaling. Regulating
tyrosine phosphorylation levels ultimately controls gene transcription, metabolism, cell growth and
differentiation, cell migration, ...
Cited by 2 - Related articles - All 2 versions

Identification of squalamine in the plasma membrane of white blood cells in the sea …

- jlr.org
SS Yun, W Li - The Journal of Lipid Research, 2007 - ASBMB
It is well established that innate mechanisms play an important role in the immunity of fish.
Antimicrobial peptides have been isolated and characterized from several species of teleosts. Here,
we report the isolation of an ...
Cited by 1 - Related articles - All 5 versions

[PDF] Zukunftsperspektiven der medikamentosen Therapie bei Adipositas


B Pichler, B Ludvik - JOURNAL FUR KARDIOLOGIE, 2003 - bernhard-ludvik.at
Kurzfassung: Adipositas und besonders die viszerale Form gelten als Wegbereiter des Metabolischen
Syn- droms, welches aufgrund der assoziierten Risikofakto- ren für die erhöhte, vorwiegend
kardiovaskuläre Mor- talität der ...
Cited by 1 - Related articles - View as HTML - BL Direct - All 12 versions

[BOOK] Good germs, bad germs: health and survival in a bacterial world


JS Sachs - 2007 - books.google.com
"'Good Germs, Bad Germs is incredibly well researched and contains a wealth of fascinating
information. It is completely up-to-date, iiitej!,i atinj!; science and health with the newest ideas
on how microbes beneficially affect ...
Cited by 1 - Related articles - All 2 versions

Drug Discovery and Protein Tyrosine Phosphatases


MAT Blaskovich - Current Medicinal Chemistry, 2009 - ingentaconnect.com
Abstract: Protein tyrosine phosphatases (PTPs) play a critical role in physiological signaling
pathways by controlling the level of tyrosine phosphorylation. The past decade has seen a vast
increase in both academic and ...
Related articles - All 2 versions


 


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