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Scholar Results 1 - 10 of about 18 citing Boulard: An interval tightly linked to but distinct from the H2 complex controls both overt.... (0.11 sec) 

Genetics of autoimmune diseases in humans and in animal models


G Morahan, L Morel - Current opinion in immunology, 2002 - Elsevier
Why are some people better able to overcome infectious diseases than others? Why
is it that in some people these normally protective responses go awry so they
develop autoimmune diseases? Over the last two decades there have been ...
Cited by 50 - Related articles - All 5 versions

A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice

- nih.gov
E Marietta, K Black, M Camilleri, P Krause, RS … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig
Dermatitis herpetiformis (DH) is an autoimmune blistering skin disorder that is
associated with gluten sensitivity. It presents as a papulovesicular rash and is
often associated with enteropathy. The rash resolves when the patient is ...
Cited by 46 - Related articles - BL Direct - All 8 versions

Genetic control of NKT cell numbers maps to major diabetes and lupus loci

- jimmunol.org
LM Esteban, T Tsoutsman, MA Jordan, D Roach … - The Journal of Immunology, 2003 - Am Assoc Immnol
Natural killer T cells are an immunoregulatory population of lymphocytes that
plays a critical role in controlling the adaptive immune system and contributes
to the regulation of autoimmune responses. We have previously reported ...
Cited by 35 - Related articles - BL Direct - All 4 versions

Dissecting autoimmune diabetes through genetic manipulation of non-obese diabetic mice


Y Yang, P Santamaria - Diabetologia, 2003 - Springer
Type 1 diabetes results from a genetically and immu- nologically complex
autoimmune process that is spe- cifically directed against the pancreatic beta
cells. Non-obese diabetic mice spontaneously develop a form of autoimmune ...
Cited by 21 - Related articles - BL Direct - All 4 versions

Lessons on autoimmune diabetes from animal models


Y Yang, P Santamaria - Clinical Science, 2006 - clinsci.org
Abbreviations: APC, antigen-presenting cell; BB, BioBreeding; CTLA-4, cytotoxic
T-lymphocyte-associated antigen-4; DCR3, decoy receptor 3; DC, dendritic cell;
GAD65, 65 kDa glutamic acid decarboxylase; HA, haemagglutinin; HLA, human ...
Cited by 18 - Related articles - Cached - BL Direct - All 10 versions

Mapping Non–Class II H2-Linked Loci for Type 1 Diabetes in Nonobese Diabetic Mice

- diabetesjournals.org
N Deruytter, O Boulard, HJ Garchon - Diabetes, 2004 - Am Diabetes Assoc
Major histocompatibility complex (MHC) plays a largely predominant role in the
genetic predisposition to type 1 diabetes, in both humans and rodents. While
class II loci have long been recognized as essential, they do not fully ...
Cited by 16 - Related articles - BL Direct - All 5 versions

Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain …


CE Mathews, RT Graser, RJ Bagley, JW … - Immunogenetics, 2003 - Springer
Abstract ALR mice are closely related to type-1 diabetes mellitus (T1DM)-prone
NOD mice. The ALR genome confers systemically elevated free radical defenses,
dom- inantly protecting their pancreatic islets from free radical ...
Cited by 16 - Related articles - BL Direct - All 3 versions

Nonobese diabetic mice and the genetics of diabetes susceptibility


EH Leiter - Current Diabetes Reports, 2005 - Springer
Introduction Knowledge of the genetic basis for type 1 diabetes (T1D)
susceptibility in humans has expanded from the major con- tribution of the major
histocompatibility complex (MHC) class II region (IDDM1 “superlocus,” ...
Cited by 12 - Related articles - All 3 versions

HLA associations in type 1 diabetes: DPB1 alleles may act as markers of other HLA-complex …


S Johansson, BA Lie, F Pociot, J Nerup, A … - Tissue antigens, 2003 - interscience.wiley.com
Abstract: Alleles at the HLA-DQB1, -DQA1 and -DRB1 loci are major determinants
for susceptibility to develop type 1 diabetes (T1D). Increasing evidence
supports that also other genes in, or near, the HLA complex contribute to ...
Cited by 11 - Related articles - BL Direct - All 4 versions

Genetics of autoimmune myasthenia gravis: the multifaceted contribution of the HLA …

- 9b01.net [PDF] 
C Vandiedonck, M Giraud, HJ Garchon - Journal of Autoimmunity, 2005 - Elsevier
The HLA complex plays a prominent role in predisposition to many autoimmune
diseases. Thus far, the highly polymorphic class I and class II loci have been
considered as the prime candidates to explain this role. There is ...
Cited by 11 - Related articles - All 5 versions


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