- ►diabetesjournals.org EA Ryan, BW Paty, PA Senior, D Bigam, E Alfadhli, NM … - Diabetes, 2005 - Am Diabetes Assoc Islet transplantation can restore endogenous β-cell function to subjects with type 1 diabetes.
Sixty-five patients received an islet transplant in Edmonton as of 1 November 2004. Their mean
age was 42.9 ± 1.2 years, their mean duration of diabetes was 27.1 ± 1.3 years, and 57% ... Cited by 532 - Related articles - All 10 versions
- ►shouxi.net AM Shapiro, C Ricordi, BJ Hering, H … - New England Journal …, 2006 - content.nejm.org AM James Shapiro, MD, Ph.D., Camillo Ricordi, MD, Bernhard J. Hering, MD, Hugh
Auchincloss, MD, Robert Lindblad, MD, R. Paul Robertson, MD, Antonio Secchi, MD, Mathias
D. Brendel, MD, Thierry Berney, MD, Daniel C. Brennan, MD, Enrico Cagliero, MD, ... Cited by 395 - Related articles - BL Direct - All 9 versions
H Kojima, M Fujimiya, K Matsumura, P Younan, H … - Nature medicine, 2003 - nature.com To explore induced islet neogenesis in the liver as a strategy for the treatment of diabetes, we
used helper-dependent adenovirus (HDAD) to deliver the pancreatic duodenal homeobox-1
gene (Ipf1; also known as Pdx-1) to streptozotocin (STZ)-treated diabetic mice. HDAD is ... Cited by 236 - Related articles - BL Direct - All 3 versions
- ►shouxi.net GS Eisenbarth, PA Gottlieb - The New England journal of medicine, 2004 - nejm.org Disease is determined by a subgroup of T cells that recognize one or more peptides of the target
organ. These peptides are bound in the groove of HLA molecules and are presented to the
T-cell receptor (TCR) of T lymphocytes. B lymphocytes stimulated by T cells produce ... Cited by 192 - Related articles - BL Direct - All 16 versions
- ►shouxi.net RP Robertson - The New England journal of medicine, 2004 - nejm.highwire.org In 1993 the Diabetes Control and Complications Trial (DCCT) established the modern standard
of care for the medical management of type 1 diabetes mellitus. 1 The DCCT randomly assigned
1441 patients to conventional or intensive treatment. The latter included multiple daily ... Cited by 174 - Related articles - All 9 versions
- ►diabetesjournals.org GC Weir, S Bonner-Weir - Diabetes, 2004 - Am Diabetes Assoc This article proposes five stages in the progression of diabetes, each of which is characterized
by different changes in ß-cell mass, phenotype, and function. Stage 1 is compensation: insulin
secretion increases to maintain normoglycemia in the face of insulin resistance and/or ... Cited by 162 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org R Gao, J Ustinov, MA Pulkkinen, K Lundin, O Korsgren, … - Diabetes, 2003 - Am Diabetes Assoc We have reproduced a previously described method for the in vitro generation of endocrine cells
in adult human pancreatic tissue culture. The aim of this study was to characterize the nature
of pancreatic progenitor cells and to identify the factors necessary for their differentiation ... Cited by 156 - Related articles - BL Direct - All 7 versions
- ►diabetesresearch.org [PDF] T Froud, C Ricordi, DA Baidal, MM Hafiz, G … - American Journal of …, 2005 - ccmjournal.org T he appropriate management of fluids, including the use of colloid therapy, in patients with acute
lung injury (ALI) and acute respiratory distress syndrome (ARDS) has been debated for decades
and remains controversial (1). The case for aggressive diuresis, suggested by prior ... Cited by 141 - Related articles - All 8 versions
E Kroon, LA Martinson, K Kadoya, AG Bang, OG … - Nature …, 2008 - novocell.com Development of a cell therapy for diabetes would be greatly aided by a renewable supply of
human ß-cells. Here we show that pancreatic endoderm derived from human embryonic stem
(hES) cells efficiently generates glucose-responsive endocrine cells after implantation ... Cited by 134 - Related articles - View as HTML - BL Direct - All 10 versions
JF Markmann, S Deng, X Huang, NM Desai, EH … - Annals of …, 2003 - pubmedcentral.nih.gov The recent report by the Edmonton group documenting restoration of insulin independence by
islet transplantation in seven consecutive patients with type 1 diabetes differed from previous
worldwide experience of only sporadic success. In the Edmonton patients, the ... Cited by 123 - Related articles - BL Direct - All 7 versions
