AE Butler, J Janson, WC Soeller, PC Butler - Diabetes, 2003 - Am Diabetes Assoc Nondiabetic obese humans adapt to insulin resistance by increasing β-cell mass. In
contrast, obese humans with type 2 diabetes have an ∼60% deficit in β-cell mass. Recent studies
in rodents reveal that β-cell mass is regulated, increasing in response to insulin ... Cited by 146 - Related articles - BL Direct - All 6 versions
- ►endojournals.org RH Straub - Endocrine reviews, 2007 - Endocrine Soc This review delineates how the effects of estrogens are dependent on criteria such as: 1) the
immune stimulus (foreign antigens or autoantigens) and subsequent antigen-specific immune
responses (eg., T cell inhibited by estrogens vs. activation of B cell); 2) the cell types ... Cited by 73 - Related articles - BL Direct - All 5 versions
P Alonso-Magdalena, S Morimoto, C … - Environmental …, 2006 - pubmedcentral.nih.gov The function of the pancreatic β-cell is the storage and release of insulin, the main hormone involved
in blood glucose homeostasis. The results in this article show that the widespread environmental
contaminant bisphenol-A (BPA) imitates 17β-estradiol (E 2 ) effects in vivo on blood ... Cited by 68 - Related articles - BL Direct - All 20 versions
JF Louet, C LeMay, F Mauvais-Jarvis - Current Atherosclerosis Reports, 2004 - Springer Introduction Type 2 diabetes mellitus is now considered a major threat to world health and is
predicted to reach epidemic proportions in the next 25 years in industrialized countries.
Indeed, the number of people with diabetes is projected to double by 2025 [1], and for ... Cited by 55 - Related articles - BL Direct - All 2 versions
A Clark, MR Nilsson - Diabetologia, 2004 - Springer The role of islet amyloidosis in the onset and progres- sion of Type 2 diabetes remains
obscure. Islet amyloid polypeptide is a 37 amino-acid, beta-cell peptide which is co-stored and
co-released with insulin. Human islet amyloid polypeptide refolds to a β-conformation and ... Cited by 51 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org M Satoh, CM Matter, H Ogita, K Takeshita, CY Wang, … - Circulation, 2007 - Am Heart Assoc Methods and Results— 17ß-Estradiol (E2, 0.5 mg/60-day release) or placebo pellet was implanted
subcutaneously into male G q transgenic (Gq) mice. After 8 weeks, E2 treatment decreased the
extent of cardiac hypertrophy and dilation and improved contractility in Gq mice. E2 ... Cited by 27 - Related articles - All 7 versions
R Muff, W Born, TA Lutz, JA Fischer - Peptides, 2004 - Elsevier The hormone calcitonin (CT) of thyroid C-cell origin, the neuropeptides α- and β-calcitonin
gene-related peptide (CGRP), the widely expressed hormone and tissue factor adrenomedullin
(AM), and amylin (AMY) that is co-produced with insulin in pancreatic β-cells, are ... Cited by 22 - Related articles - All 4 versions
- ►endojournals.org H Zhang, AM Ackermann, GA Gusarova, D Lowe … - Molecular …, 2006 - Endocrine Soc The FoxM1 transcription factor is highly expressed in proliferating cells and activates several
cell cycle genes, although its requirement appears to be limited to certain tissue types. Embryonic
hepatoblast-specific inactivation of Foxm1 results in a dramatic reduction in liver ... Cited by 20 - Related articles - BL Direct - All 4 versions
H Qin, W Ting-huai, LU Wen-sheng, MU Pan-wei, Y … - Chinese medical journal, 2006 - cmj.org Background Estrogen might play an important role in type 2 diabetes mellitus pathogenesis.
A number of polymorphisms have been reported in the estrogen receptor alpha (ERメ) gene
(also named ESR1), including the XbaI and PvuII restriction enzyme polymorphisms of ... Cited by 12 - Related articles - Cached - BL Direct - All 9 versions
