- ►diabetesjournals.org J Tonelli, W Li, P Kishore, UB Pajvani, E … - Diabetes, 2004 - Am Diabetes Assoc Whereas thiazolidinediones (TZDs) are known to rapidly improve insulin action in
animals, short durations of TZD therapy have never been studied in humans. Among
the many known actions of TZDs, increased circulating levels of the high ... Cited by 142 - Related articles - BL Direct - All 5 versions
M Krebs, M Roden - Diabetes Obesity and Metabolism, 2005 - pt.wkhealth.com Increased body fat content correlates with insulin resistance and is a key
feature of type 2 diabetes. Excessive intake of fat results in deposition of
lipids not only in fat tissue but also in skeletal muscle and liver. ... Cited by 39 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org M Hawkins, J Tonelli, P Kishore, D Stein, E … - Diabetes, 2003 - Am Diabetes Assoc Increased circulating free fatty acids (FFAs) inhibit both hepatic and
peripheral insulin action. Because the loss of effectiveness of glucose to
suppress endogenous glucose production and stimulate glucose uptake ... Cited by 31 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org J Shao, L Qiao, RC Janssen, M Pagliassotti, … - Diabetes, 2005 - Am Diabetes Assoc Acute hyperglycemia normally suppresses hepatic glucose production (HGP) and
gluconeogenic gene expression. Conversely, chronic hyperglycemia is accompanied
by progressive increases in basal HGP and is a major contributor to ... Cited by 29 - Related articles - All 5 versions
- ►physiology.org R Basu, WF Schwenk, RA Rizza - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc To determine whether regulation of fasting endogenous glucose production (EGP)
and glucose disappearance (R d ) are both abnormal in people with type 2
diabetes, EGP and R d were measured in 7 "severe" (SD), 9 "mild" (MD), and ... Cited by 28 - Related articles - All 3 versions
- ►endojournals.org DA Elder, RL Prigeon, RP Wadwa, LM Dolan, … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Context: Type 2 diabetes mellitus (T2DM) is estimated to account for 10–45% of
incident pediatric diabetes cases. ... Objective: Our objective was to
characterize the metabolic defects underlying T2DM in adolescents and young ... Cited by 21 - Related articles - BL Direct - All 6 versions
- ►physiology.org A Vella, AS Reed, N Charkoudian, P Shah, R … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc To determine whether, in the presence of constant insulin concentrations, a
change in glucose concentrations results in a reciprocal change in endogenous
glucose production (EGP), glucagon ( 130 ng/l) and insulin ( 65 pmol/l) ... Cited by 18 - Related articles - BL Direct - All 4 versions
MC Moore, AD Cherrington, DH Wasserman - Best Practice & Research Clinical Endocrinology & …, 2003 - Elsevier Precise regulation of hepatic and peripheral glucose uptake is essential to
preserve glucose homeostasis. The liver extracts 1/3 of an oral glucose load,
skeletal muscle extracts 1/3, and other tissues, particularly the central ... Cited by 18 - Related articles - All 6 versions
AF Kernohan, N Sattar, T Hilditch, SJ … - CLINICAL ENDOCRINOLOGY-OXFORD-, 2007 - pt.wkhealth.com Background: Low-dose hormone replacement therapy (HRT) has attracted interest
for the treatment of postmenopausal symptoms in diabetes because of concerns
about increased risk of coronary heart disease (CHD) and stroke with ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org Y Fujimoto, TP Torres, EP Donahue, M Shiota - Diabetes, 2006 - Am Diabetes Assoc The effect of restoration of normoglycemia by a novel sodium-dependent glucose
transporter inhibitor (T-1095) on impaired hepatic glucose uptake was examined
in 14-week-old Zucker diabetic fatty (ZDF) rats. The nontreated group ... Cited by 14 - Related articles - BL Direct - All 5 versions
