N Houstis, ED Rosen, ES Lander - Nature, 2006 - cns-alumni.bu.edu Insulin resistance is a cardinal feature of type 2 diabetes and is
characteristic of a wide range of other clinical and experimental settings.
Little is known about why insulin resistance occurs in so many contexts. Do ... Cited by 355 - Related articles - View as HTML - BL Direct - All 9 versions
CWG Redman, IL Sargent - Placenta, 2003 - Elsevier The central role of the placenta in the pathogenesis of pre-eclampsia is
undisputed. The evidence that maternal syndrome of pre-eclampsia is caused by a
maternal systemic inflammatory response (MSIR) is reviewed. The polymorphic ... Cited by 172 - Related articles - BL Direct - All 11 versions
- ►endojournals.org R Retnakaran, AJG Hanley, N Raif, PW … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc Acute-phase biomarkers such as C-reactive protein (CRP) and IL-6 have emerged as
predictors of incident type 2 diabetes mellitus, implicating chronic subclinical
inflammation as a factor in the pathophysiology of diabetes. Gestational ... Cited by 95 - Related articles - BL Direct - All 5 versions
RB Ness, BM Sibai - American journal of obstetrics and gynecology, 2006 - Elsevier Intrauterine growth restriction (IUGR) and preeclampsia differ in their
association with maternal disease but share a similar placental pathology.
Moreover, mothers who have had pregnancies complicated by preeclampsia or ... Cited by 79 - Related articles - All 21 versions
VA Rodie, DJ Freeman, N Sattar, IA Greer - Atherosclerosis, 2004 - Elsevier Complications of pregnancy, particularly pre-eclampsia (PET) and intra-uterine
growth restriction (IUGR) have been associated with future maternal
cardiovascular disease (CVD). Pre-eclampsia, characterised by insulin ... Cited by 80 - Related articles - All 13 versions
- ►diabetesjournals.org M Wolf, L Sandler, K Hsu, K Vossen-Smirnakis … - Diabetes Care, 2003 - Am Diabetes Assoc RESULTS—First-trimester CRP levels were significantly increased among women
who subsequently developed GDM compared with control subjects (3.1 vs. 2.1 mg/l,
P < 0.01). The risk of developing GDM among women in the highest CRP ... Cited by 74 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org T Radaelli, A Varastehpour, P Catalano, S … - Diabetes, 2003 - Am Diabetes Assoc A physiological state of insulin resistance is required to preferentially direct
maternal nutrients toward the feto-placental unit, allowing adequate growth of
the fetus. When women develop gestational diabetes mellitus (GDM), insulin ... Cited by 69 - Related articles - BL Direct - All 5 versions
- ►nih.gov E Podjarny, C Baylis, G Losonczy - Seminars in perinatology, 1999 - Elsevier Some of the maternal symptoms of preeclampsia can be produced by uterine
ischemia, although no quadriped spontaneously exhibits this disease. It may be
that the combination of upright posture and uteroplacental ischemia are ... Cited by 70 - Related articles - BL Direct - All 12 versions
- ►endojournals.org LA Barbour, J Shao, L Qiao, W Leitner, M … - Endocrinology, 2004 - Endocrine Soc The insulin resistance of normal pregnancy is necessary to divert fuels to the
fetus to meet fetal growth demands and is mediated by placental hormones. We
recently demonstrated that human placental GH (hPGH) can trigger severe ... Cited by 59 - Related articles - BL Direct - All 4 versions
PM Catalano - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc "Obesity is a chronic disease, prevalent in both developed and developing
countries, and affecting children as well as adults. Indeed, it is now so common
that it is replacing the more traditional public health concerns, including ... Cited by 55 - Related articles - BL Direct - All 5 versions
