- ►mac.com [PDF] - Free from Publisher S Clement, SS Braithwaite, MF Magee, A … - Diabetes Care, 2004 - Am Diabetes Assoc Diabetes increases the risk for disorders that predispose individuals to
hospitalization, including coronary artery, cerebrovascular and peripheral
vascular disease, nephropathy, infection, and lower-extremity amputations. ... Cited by 409 - Related articles - BL Direct - All 10 versions
L Zheng, C Szabó, TS Kern - Diabetes, 2004 - Am Diabetes Assoc The current study investigated the role of poly(ADP-ribose) polymerase (PARP) in
the development of diabetic retinopathy. Activity of PARP was increased in whole
retina and in endothelial cells and pericytes of diabetic rats. ... Cited by 98 - Related articles - BL Direct - All 5 versions
- ►fasebj.org [PDF] M Artwohl, M Roden, W Waldhausl, A … - The FASEB Journal, 2003 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.03-0301fje. Published online
November 3, 2003. Free fatty acids trigger apoptosis and inhibit cell cycle ... Cited by 84 - Related articles - BL Direct - All 5 versions
JK Krady, A Basu, CM Allen, Y Xu, KF … - Diabetes, 2005 - Am Diabetes Assoc Diabetes leads to vascular leakage, glial dysfunction, and neuronal apoptosis
within the retina. The goal of the studies reported here was to determine the
role that retinal microglial cells play in diabetic retinopathy and assess ... Cited by 81 - Related articles - All 10 versions
- ►diabetesjournals.org HP Hammes, J Lin, P Wagner, Y Feng, F vom … - Diabetes, 2004 - Am Diabetes Assoc Pericyte loss is an early pathologic feature of diabetic retinopathy,
consistently present in retinae of diabetic humans and animals. Because pericyte
recruitment and endothelial cell survival are controlled, in part, by the ... Cited by 79 - Related articles - BL Direct - All 4 versions
RA Kowluru, P Koppolu, S Chakrabarti, S … - Free radical research, 2003 - informahealthcare.com Oxidative stress is increased in the retina in diabetes, and long-term
administration of antioxidants inhibits the development of retinopathy in
diabetic rats. The purpose of this study is to determine how diabetes ... Cited by 75 - Related articles - BL Direct - All 8 versions
T Mandrup-Poulsen - Biochemical pharmacology, 2003 - Elsevier Failure of insulin producing pancreatic β-cells is a common characteristic of
type 1 (insulin-dependent) and type 2 (insulin non-dependent) diabetes mellitus.
Accumulating evidence suggests that programmed cell death (apoptosis) is ... Cited by 71 - Related articles - All 5 versions
Z Dagher, YS Park, V Asnaghi, T Hoehn, C … - Diabetes, 2004 - Am Diabetes Assoc The polyol (sorbitol) pathway of glucose metabolism is activated in many cell
types when intracellular glucose concentrations are high, and it can generate
cellular stress through several mechanisms. The role of the polyol pathway ... Cited by 65 - Related articles - BL Direct - All 4 versions
- ►physiology.org S Chen, ZA Khan, M Cukiernik, S Chakrabarti - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc Increased extracellular matrix protein production leading to structural
abnormalities is a characteristic feature of chronic diabetic complications. We
previously showed that high glucose in endothelial cell culture leads to ... Cited by 63 - Related articles - BL Direct - All 5 versions
KV Ramana, B Friedrich, S Srivastava, A … - Diabetes, 2004 - Am Diabetes Assoc Activation of the polyol pathway has been linked to the development of secondary
diabetic complications. However, the underlying molecular mechanisms remain
unclear. To probe the contribution of this pathway, we examined whether ... Cited by 61 - Related articles - BL Direct - All 4 versions
