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Scholar Results 1 - 10 of about 35 citing Freshwater: Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia.... (0.08 sec) 

Regulation of cyclooxygenase-2 expression in monocytes by ligation of the …


N Shanmugam, YS Kim, L Lanting, R Natarajan - Journal of Biological …, 2003 - ASBMB
Cyclooxygenase-2 (COX-2) enzyme and its inflammatory products such as prostaglandin E 2 (PGE 2 )
have been implicated in the pathogenesis of several inflammatory diseases. However their role in
diabetic vascular disease is ...
Cited by 83 - Related articles - BL Direct - All 4 versions

Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose …


NA Calcutt, JD Freshwater, AP Mizisin - Diabetologia, 2004 - Springer
Aims/hypothesis. Sensory neuropathy in diabetic pa- tients frequently presents itself as progressive
loss of thermal perception, while some patients describe con- current spontaneous pain, allodynia or
hyperalgesia. Diabetic rats develop ...
Cited by 48 - Related articles - BL Direct - All 7 versions

Poly (ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory …


O Ilnytska, VV Lyzogubov, MJ Stevens, VR Drel, N … - Diabetes, 2006 - Am Diabetes Assoc
Poly(ADP-ribose) polymerase (PARP) activation is emerging as a fundamental mechanism in the
pathogenesis of diabetes complications including diabetic neuropathy. This study evaluated the role
of PARP in diabetic sensory ...
Cited by 28 - Related articles - BL Direct - All 10 versions

Microdialysis in pain research

- itsmenotyou.com [PDF] 
CO Stiller, BK Taylor, B Linderoth, H Gustafsson, A … - Advanced drug delivery …, 2003 - Elsevier
In vivo microdialysis has been used in preclinical pain research for more than a decade. This
valuable tool allows correlations between nociceptive behavior and neurotransmitter release in
pain-related CNS sites. However, ...
Cited by 18 - Related articles - BL Direct - All 7 versions

Experimental models of painful diabetic neuropathy


NA Calcutt - Journal of the neurological sciences, 2004 - Elsevier
Diabetes mellitus is one of the most rapidly growing health concerns in the developed world due to
the persistence of type 1 (insulin-deficient) diabetes and the dramatic increase in type 2 (insulin-
resistant) diabetes that is ...
Cited by 15 - Related articles - All 6 versions

Current and future strategies for the management of diabetic neuropathy

- adisonline.com [PDF] 
RA Malik - Treatments in Endocrinology, 2003 - ingentaconnect.com
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Cited by 15 - Related articles - BL Direct - All 4 versions

Pathogenesis of spinally mediated hyperalgesia in diabetes


KM Ramos, Y Jiang, CI Svensson, NA Calcutt - Diabetes, 2007 - Am Diabetes Assoc
Hyperalgesia to noxious stimuli is accompanied by increased spinal cyclooxygenase (COX)-2 protein in
diabetic rats. The present studies were initiated to establish causality between increased spinal
COX-2 activity and hyperalgesia ...
Cited by 13 - Related articles - BL Direct - All 5 versions

Effect of etodolac, a COX-2 inhibitor, on neuropathic pain in a rat model


H Suyama, M Kawamoto, S Gaus, O Yuge - Brain research, 2004 - Elsevier
Etodolac, a cyclooxygenase-2 inhibitor, may alleviate nociceptive pain and inhibit the activation of
osteoclasts. The aim of the present study was to determine whether etodolac can alleviate
heat-evoked hyperalgesia and ...
Cited by 11 - Related articles - All 3 versions

Future treatments for diabetic neuropathy: clues from experimental neuropathy


NA Calcutt - Current Diabetes Reports, 2002 - Springer
Introduction There are an estimated 150 million diabetic patients in the world and the incidence of
diabetes is increasing in most countries [1]. Diabetes ranks as the sixth leading cause of death in
the United States; this is usually ...
Cited by 9 - Related articles - BL Direct - All 2 versions

Inhibition of type 1 diabetic hyperalgesia in streptozotocin-induced Wistar versus …


BH Gabra, O Benrezzak, LH Pheng, D Duta, P … - … of Neuropathology & …, 2005 - journals.lww.com
From the Department of Pharmacology (BHG, PS), Faculty of Medicine, University of Sherbrooke,
Sherbrooke; IPS Pharma, Inc. (BHG, OB, LHP, DD, PD, PS, FN, BB), Sherbrooke; and Laval Hospital
Research Center-Québec Heart and ...
Cited by 9 - Related articles - BL Direct - All 4 versions


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