AP Somlyo, AV Somlyo - Physiological reviews, 2003 - Am Physiological Soc Recognition that calcium is the intracellular messenger that triggers muscle
contraction (144) by binding, in striated muscles, to the Ca-binding protein
troponin (88) eventually led to the realization that Ca-regulated myosin II ... Cited by 699 - Related articles - BL Direct - All 12 versions
- ►endojournals.org R Muniyappa, M Montagnani, KK Koh, MJ … - Endocrine reviews, 2007 - Endocrine Soc Insulin has important vascular actions to stimulate production of nitric oxide
from endothelium. This leads to capillary recruitment, vasodilation, increased
blood flow, and subsequent augmentation of glucose disposal in classical ... Cited by 99 - Related articles - BL Direct - All 5 versions
X Bi, M Baudry, J Liu, Y Yao, L Fu, F Brucher, … - Journal of Biological Chemistry, 2004 - ASBMB Inflammatory responses involving microglia, the resident macrophages of the
brain, are thought to contribute importantly to the progression of Alzheimer's
disease (AD) and possibly other neurodegenerative disorders. The present ... Cited by 47 - Related articles - BL Direct - All 5 versions
- ►physiology.org J Duan, HY Zhang, SD Adkins, BH Ren, FL … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc This study characterized the cardiac contractile function and IGF-I response in
a transgenic diabetic mouse model. Mechanical properties were evaluated in
cardiac myocytes from OVE26 diabetic and FVB wild-type mice, including peak ... Cited by 42 - Related articles - BL Direct - All 4 versions
M Rolli-Derkinderen, V Sauzeau, L Boyer, E … - Circulation research, 2005 - Am Heart Assoc Abstract—cAMP and cyclic GMP-dependent kinases phosphorylate the small G
protein RhoA on Ser188. We have previously demonstrated that phosphorylation of
Ser188 inhibits RhoA-dependent functions and positively regulates RhoA ... Cited by 41 - Related articles - All 10 versions
- ►physiology.org SA Cooper, A Whaley-Connell, J Habibi, Y Wei … - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc Hypertension commonly occurs in conjunction with insulin resistance and other
components of the cardiometabolic syndrome. Insulin resistance plays a
significant role in the relationship between hypertension, Type 2 diabetes ... Cited by 40 - Related articles - BL Direct - All 4 versions
TM Lincoln, X Wu, H Sellak, N Dey, CS Choi - Front Biosci, 2006 - bioscience.org 1. Abstract 2. Introduction 3. Basic mechanisms underlying VSMC growth and
differentiation 4. Role of the cGMP pathway in regulating VSMC growth and
phenotype 5. Role of cGMP and PKG in VSMC-specific gene expression in ... Cited by 36 - Related articles - View as HTML - All 3 versions
H Ohkawara, T Ishibashi, T Sakamoto, K … - Journal of Biological Chemistry, 2005 - ASBMB RhoA plays a critical signaling role in thrombin-induced endothelial
dysfunction. The possible thrombin regulation of geranylgeranylation, a lipid
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SN Stas, FA El-Atat, JR Sowers - Reviews in Endocrine & Metabolic Disorders, 2004 - Springer Hypertension, diabetes and obesity are commonly co- existed. Hypertension is as
up to three times as frequent in diabetic patients as non-diabetics [1]. It
significantly increases the risk for microvascular disease as well as car- ... Cited by 13 - Related articles - BL Direct - All 3 versions
- ►physiology.org JH Lee, L Ragolia - American Journal of Physiology- Cell Physiology, 2006 - Am Physiological Soc Insulin resistance, a major factor in the development of type 2 diabetes, is
known to be associated with defects in blood vessel relaxation. The role of Akt
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