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Scholar Results 1 - 10 of about 22 citing Thirone: Modulation of growth hormone signal transduction in kidneys of streptozotocin-induced.... (0.09 sec) 

Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent …

- nih.gov
JC He, M Husain, M Sunamoto, VD D'Agati, ME … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig
In collapsing focal segmental glomerulosclerosis (FSGS) of HIV-associated
nephropathy (HIVAN), podocytes exhibit a high proliferation rate and loss of
differentiation markers. We have found previously that the nef gene of ...
Cited by 66 - Related articles - BL Direct - All 6 versions

[PDF] Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and …


J ŽDYCHOVÁ, R Komers - Physiol. Res, 2005 - biomed.cas.cz
Summary In addition to a number of deleterious effects on cellular integrity and
functions, diabetic metabolic milieu has been implicated in a rapidly growing
number of alterations in signal transduction. In this review we focus on ...
Cited by 42 - Related articles - View as HTML - All 5 versions

Suppressors of cytokine signaling in health and disease


JC Tan, R Rabkin - Pediatric Nephrology, 2005 - Springer
Abstract Cytokines consist of a large family of secreted proteins, including
pro-inflammatory agents, growth hormone and erythropoietin, that utilize the
Janus kinase (JAK) signal transducer and activator of transcription (STAT) ...
Cited by 38 - Related articles - All 2 versions

Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, …

- physiology.org
J Kaput, KG Klein, EJ Reyes, WA Kibbe, CA … - Physiological Genomics, 2004 - Am Physiological Soc
The incidence and severity of obesity and type 2 diabetes are increasing in
Western societies. The progression of obesity to type 2 diabetes is gradual with
overlapping symptoms of insulin resistance, hyperinsulinemia, ...
Cited by 23 - Related articles - BL Direct - All 2 versions

New concepts: growth hormone, insulin-like growth factor-I and the kidney


R Rabkin, F Schaefer - Growth Hormone & IGF Research, 2004 - Elsevier
Both growth hormone (GH) and IGF-1 have major effects on normal kidney growth,
structure and function and participate in the pathogenesis of certain kidney
diseases. Furthermore when the kidneys fail there are profound changes in ...
Cited by 19 - Related articles - All 3 versions

The physiological and pathophysiological roles of the GH/IGF-axis in the kidney: lessons …


V Cingel-Ristić, A Flyvbjerg, SLS Drop - Growth hormone & IGF research, 2004 - Elsevier
The growth hormone (GH)/insulin-like growth factor (IGF) system plays an
important role in renal development, growth, function and pathophysiology. IGF-I
has been associated with renal/glomerular hypertrophy and compensatory ...
Cited by 16 - Related articles - All 4 versions

Infliximab reverses steatosis and improves insulin signal transduction in liver of rats fed a …

- endocrinology-journals.org
R Barbuio, M Milanski, MB Bertolo, MJ Saad, … - Journal of Endocrinology, 2007 - Soc Endocrinology
Non-alcoholic fatty liver disease, induced by nutritional factors, is one of the
leading causes of hepatic dysfunction in the modern world. The activation of
proinflammatory signaling in the liver, which is induced by systemic and ...
Cited by 14 - Related articles - BL Direct - All 3 versions

Identification of the glomerular podocyte as a target for growth hormone action

- endojournals.org
GR Reddy, MJ Pushpanathan, RF Ransom, LB … - Endocrinology, 2007 - Endocrine Soc
GH excess in both the human and transgenic animal models is characterized by
significant changes in blood pressure and renal function. The GH/GH receptor
(GHR) axis is also implicated in the development of diabetic nephropathy. ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Role of oxidative stress in age-associated chronic kidney pathologies


C Percy, B Pat, P Poronnik, G Gobe - Advances in Chronic Kidney Disease, 2005 - Elsevier
The kidneys exhibit age-associated deterioration in function via a loss of 20%
to 25% kidney mass, particularly from the renal cortex and increased fibrosis.
Oxidative stress has been found to mediate age-associated renal cell injury ...
Cited by 11 - Related articles - All 10 versions

Oxidant driven signaling pathways during diabetes: role of Rac1 and modulation of protein …


DP Poladia, JA Bauer - Biochimie, 2004 - Elsevier
Results. – We detected significant increases in protein 3-nitrotyrosine in
both urothelium and smooth muscle regions during diabetes, demonstrating an
increased prevalence of reactive nitrogen species. In light of nitric oxide ...
Cited by 9 - Related articles - All 3 versions


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