L Tian, SA Greenberg, SW Kong, J Altschuler, … - Proceedings of the National Academy of Sciences, 2005 - National Acad Sciences Accurate and rapid identification of perturbed pathways through the analysis of
genome-wide expression profiles facilitates the generation of biological
hypotheses. We propose a statistical framework for determining whether a ... Cited by 171 - Related articles - BL Direct - All 16 versions
- ►nih.gov CS Stump, KR Short, ML Bigelow, JM Schimke … - Proceedings of the National Academy of Sciences of …, 2003 - National Acad Sciences Mitochondria are the primary site of skeletal muscle fuel metabolism and ATP
production. Although insulin is a major regulator of fuel metabolism, its effect
on mitochondrial ATP production is not known. Here we report increases in ... Cited by 133 - Related articles - BL Direct - All 10 versions
- ►endojournals.org X Wang, Z Hu, J Hu, J Du, WE Mitch - Endocrinology, 2006 - Endocrine Soc Conditions such as acidosis, uremia, and sepsis are characterized by insulin
resistance and muscle wasting, but whether the insulin resistance associated
with these disorders contributes to muscle atrophy is unclear. We examined ... Cited by 54 - Related articles - BL Direct - All 4 versions
B Bammens, P Evenepoel, H Keuleers, K … - Protein-bound Solute P-cresol: Generation, Elimination …, 2005 - books.google.com Chapter 9 Introduction When in the nineteen sixties dialysis strategies as a
maintenance therapy for stage 5 renal disease were introduced in clinical
practice, the quality of life and survival of patients improved ... Cited by 53 - Related articles - BL Direct - All 5 versions
- ►shouxi.net YW Asmann, CS Stump, KR Short, JM Coenen- … - Diabetes, 2006 - Am Diabetes Assoc We investigated whether previously reported muscle mitochondrial dysfunction and
altered gene transcript levels in type 2 diabetes might be secondary to abnormal
blood glucose and insulin levels rather than an intrinsic defect of type 2 ... Cited by 49 - Related articles - BL Direct - All 5 versions
J Szendroedi, AI Schmid, M Chmelik, C Toth, … - PLoS Med, 2007 - medicine.plosjournals.org We measured G-6-P, ATP synthetic flux (ie, synthesis) and lipid contents of
skeletal muscle with 31 P/ 1 H magnetic resonance spectroscopy in ten patients
with T2DM and in two control groups: ten sex-, age-, and body mass-matched ... Cited by 40 - Related articles - Cached - All 9 versions
- ►physiology.org KS Nair, A Jaleel, YW Asmann, KR Short, S … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Proteomics is the comprehensive and systematic study of proteins, which are
functional molecules. Although proteins are products of gene expression, there
are more proteins than genes due to the posttranslational modifications of ... Cited by 27 - Related articles - BL Direct - All 3 versions
M Aragno, R Mastrocola, MG Catalano, E … - Diabetes, 2004 - Am Diabetes Assoc Alongside increased proteolysis, the inability to repair damaged skeletal muscle
is a characteristic feature of uncontrolled diabetes. This study evaluates the
role of oxidative stress in muscle-specific gene regulatory regions and ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►nrc-cnrc.gc.ca [PDF] EP Wijekoon, C Skinner, ME Brosnan, JT … - Canadian journal of physiology and pharmacology, 2004 - article.pubs.nrc-cnrc.gc.ca Abstract: We investigated amino acid metabolism in the Zucker diabetic fatty
(ZDF Gmi fa/fa) rat during the prediabetic insulin-resistant stage and the frank
type 2 diabetic stage. Amino acids were measured in plasma, liver, and ... Cited by 23 - Related articles - BL Direct - All 6 versions
LB Pupim, PJ Flakoll, KM Majchrzak, DLA Guy, … - Kidney international, 2005 - nature.com In this study, we examined whole-body and skeletal muscle protein metabolism in
6 CHD patients with type 2 (T2) DM (2 male, 44.4 6.1 years old, 2 white/4
African American HbA 1 C = 9.5 1.1%), and 6 non-DM CHD patients (2 male, ... Cited by 23 - Related articles - BL Direct - All 4 versions
