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Scholar Results 1 - 10 of about 54 citing Turnbull: Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding.... (0.09 sec) 

Appetite control

- endocrinology-journals.org
K Wynne, S Stanley, B McGowan, S Bloom - Journal of Endocrinology, 2005 - Soc Endocrinology
Our understanding of the physiological systems that regulate food intake and
body weight has increased immensely over the past decade. Brain centres,
including the hypothalamus, brainstem and reward centres, signal via ...
Cited by 173 - Related articles - All 4 versions

Hormonal regulation of food intake

- physiology.org
S Stanley, K Wynne, B McGowan, S Bloom - Physiological reviews, 2005 - Am Physiological Soc
Our knowledge of the physiological systems controlling energy homeostasis has
increased dramatically over the last decade. The roles of peripheral signals
from adipose tissue, pancreas, and the gastrointestinal tract reflecting ...
Cited by 88 - Related articles - BL Direct - All 7 versions

The level of NPY receptor mRNA expression in diet-induced obese and resistant mice


XF Huang, M Han, LH Storlien - Molecular Brain Research, 2003 - Elsevier
Some mice become obese whereas others remain lean when raised on a high-energy
diet. This study examined the levels of neuropeptide Y (NPY), and of Y1, Y2, Y5
and leptin receptor mRNA expression in the hypothalamic arcuate nucleus ...
Cited by 44 - Related articles - All 4 versions

Anabolic neuropeptides


G Williams, XJ Cai, JC Elliott, JA Harrold - Physiology & behavior, 2004 - Elsevier
Neuropeptide Y (NPY) neurons in the hypothalamic arcuate nucleus (ARC) are
inhibited by leptin and insulin, and thus are stimulated in states of energy
deficit and fat loss, eg, underfeeding. NPY neuronal overactivity ...
Cited by 42 - Related articles - All 3 versions

Characterization of neuropeptide Y (NPY) Y5 receptor-mediated obesity in mice: chronic …

- endojournals.org
S Mashiko, A Ishihara, H Iwaasa, H Sano, Z … - Endocrinology, 2003 - Endocrine Soc
To clarify the role of the neuropeptide Y (NPY) Y5 receptor subtype in energy
homeostasis, the effect of the intracerebroventricular infusion of a selective
Y5 agonist, D-Trp 34 NPY, was investigated in C57BL/6J mice. ...
Cited by 38 - Related articles - BL Direct - All 3 versions

A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated …

- nih.gov
A Ishihara, A Kanatani, S Mashiko, T Tanaka, … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences
Neuropeptide Y (NPY) is thought to have a major role in the physiological
control of energy homeostasis. Among five NPY receptors described, the NPY Y5
receptor (Y5R) is a prime candidate to mediate some of the effects of NPY ...
Cited by 32 - Related articles - BL Direct - All 10 versions

The hypothalamus and obesity


PJ King - Current Drug Targets, 2005 - ingentaconnect.com
Abstract: Obesity, a condition already at epidemic proportions in the developed
world, is largely attributable to an indulgent lifestyle. Biologically we feel
hunger more acutely than feeling 'full-up' (satiety). The discovery over a ...
Cited by 29 - Related articles - All 3 versions

A potent and selective NPY Y5 antagonist reduces food intake but not through blockade of …


O Della-Zuana, L Revereault, A Beck- … - International Journal of Obesity, 2004 - nature.com
METHODS AND RESULTS: S 25585 was shown to be a high-affinity antagonist of the
NPY Y 5 receptor subtype (IC 50 5 nM) with no significant affinity toward other
NPY receptor subtypes and over 40 other receptors, channels or uptake ...
Cited by 23 - Related articles - BL Direct - All 5 versions

[PDF] Neuropeptide Y Y5 receptor antagonists as anti-obesity drugs


NR Levens, O Della-Zuana - Current Opinion in Investigational Drugs, 2003 - biomedcentral.com
Neuropeptide Y (NPY) is present in the hypothalamus, where it is believed to
play a key role in the control of food intake. Evidence for this assertion has
come from studies demonstrating that acute administration of NPY into the ...
Cited by 20 - Related articles - View as HTML - BL Direct - All 3 versions

Neuropeptide Y in normal eating and in genetic and dietary-induced obesity

- royalsocietypublishing.org
B Beck - Philosophical Transactions B, 2006 - rstb.royalsocietypublishing.org
Neuropeptide Y (NPY) is one the most potent orexigenic peptides found in the
brain. It stimulates food intake with a preferential effect on carbohydrate
intake. It decreases latency to eat, increases motivation to eat and delays ...
Cited by 19 - Related articles - BL Direct - All 10 versions


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