- ►ahajournals.org P Poirier, TD Giles, GA Bray, Y Hong, JS … - Circulation, 2006 - Am Heart Assoc Obesity is becoming a global epidemic in both children and adults. It is
associated with numerous comorbidities such as cardiovascular diseases (CVD),
type 2 diabetes, hypertension, certain cancers, and sleep ... Cited by 262 - Related articles - All 10 versions
P Trayhurn - Acta Physiologica Scandinavica, 2005 - interscience.wiley.com White adipose tissue (WAT) is now recognized as a major endocrine and secretory
organ, releasing a wide range of protein factors and signals termed adipokines
– in addition to fatty acids and other lipid moieties. A paradigm shift ... Cited by 155 - Related articles - BL Direct - All 7 versions
P Trayhurn, I Wood - Biochemical Society Transactions, 2005 - bst.portlandpress.com White adipose tissue (WAT) is a major endocrine and secretory organ, which
releases a wide range of protein signals and factors termed adipokines. A number
of adipokines, including leptin, adiponectin, tumour necrosis factor a, ... Cited by 143 - Related articles - Cached - BL Direct - All 10 versions
KN Frayn, F Karpe, BA Fielding, IA … - International Journal of Obesity, 2003 - nature.com Adipose tissue is now recognised as a highly active metabolic and endocrine
organ. Great strides have been made in uncovering the multiple functions of the
adipocyte in cellular and molecular detail, but it is essential to remember ... Cited by 129 - Related articles - BL Direct - All 3 versions
GD Tan, BA Fielding, JM Currie, SM … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: We investigated the effects of rosiglitazone on NEFA
and triglyceride metabolism in type 2 diabetes. Methods: In a double-blind,
placebo-con- trolled, cross-over study of rosiglitazone in diet-treated ... Cited by 85 - Related articles - All 2 versions
KN Frayn - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press Obesity is a risk factor for the development of type 2 diabetes and CVD. Is
adipose tissue the culprit in the relationship between obesity and metabolic
disease? It is certainly possible to argue that adipose tissue function is ... Cited by 47 - Related articles - All 5 versions
P Trayhurn, B Wang, IS Wood - British Journal of Nutrition, 2008 - Cambridge Univ Press White adipose tissue is a key endocrine and secretory organ, releasing multiple
adipokines, many of which are linked to inflammation and immu- nity. During the
expansion of adipose tissue mass in obesity there is a major inflammatory ... Cited by 40 - Related articles - All 3 versions
ES Freedland - Nutr Metab, 2004 - biomedcentral.com Abstract There are likely many scenarios and pathways that can lead to metabolic
syndrome. This paper reviews mechanisms by which the accumulation of visceral
adipose tissue (VAT) may contribute to the metabolic syndrome, and explores ... Cited by 36 - Related articles - View as HTML - All 14 versions
GH Goossens - Physiology & Behavior, 2008 - Elsevier Research of the past decade has increased our understanding of the role adipose
tissue plays in health and disease. Adipose tissue is now recognized as a highly
active metabolic and endocrine organ. Adipocytes are of importance in ... Cited by 37 - Related articles - All 4 versions
G Riccardi, P Aggett, F Brighenti, N … - European Journal of Nutrition, 2004 - Springer ■ Summary Background Insulin sensitivity is a key function in hu- man
metabolism because it has a crucial role in the development of disease that are
increasingly com- mon in modern society. Impaired insulin sensitivity is an ... Cited by 29 - Related articles - BL Direct - All 6 versions
