- ►rupress.org S Turley, L Poirot, M Hattori, C Benoist, D … - Journal of Experimental Medicine, 2003 - jem.rupress.org The prelude to type-1 diabetes is leukocyte infiltration into the pancreatic
islets, or insulitis. This process begins in pancreatic lymph nodes when T
lymphocytes reactive to islet ß cells encounter antigen-presenting cells ... Cited by 143 - Related articles - BL Direct - All 6 versions
- ►direct-ms.org [PDF] A Giulietti, C Gysemans, K Stoffels, E Etten, … - Diabetologia, 2004 - Springer Aims/hypothesis. 1,25-dihydroxyvitamin D 3 , the ac- ... Keywords Vitamin D ·
Type 1 diabetes · NOD · Islets · Macrophage · Prevention · Rickets ...
Received: 27 July 2003 / Revised: 27 November 2003 Published online: 31 ... Cited by 74 - Related articles - BL Direct - All 6 versions
T Izumi, H Yokota-Hashimoto, S Zhao, J Wang … - Diabetes, 2003 - Am Diabetes Assoc Autosomal dominant diabetes in the Akita mouse is caused by mutation of the
insulin 2 gene, whose product replaces a cysteine residue that is engaged in the
formation of an intramolecular disulfide bond. These heterozygous mice ... Cited by 48 - Related articles - BL Direct - All 5 versions
K Haskins, B Bradley, K Powers, V Fadok, S … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2003 - interscience.wiley.com Abstract: We have been investigating the effects of preventing oxidative stress
on pathogenesis and complications of type 1 diabetes in the NOD mouse model. Our
studies have shown that damage caused by oxidative stress is higher in ... Cited by 37 - Related articles - BL Direct - All 5 versions
- ►hematologylibrary.org P Sen, MA Wallet, Z Yi, Y Huang, M … - Blood, 2007 - bloodjournal.hematologylibrary.org Dendritic cells (DCs) play a key role in immune homeostasis and maintenance of
self-tolerance. Tolerogenic DCs can be established by an encounter with
apoptotic cells (ACs) and subsequent inhibition of maturation and effector ... Cited by 37 - Related articles - BL Direct - All 8 versions
TP DiLorenzo, DV Serreze - Immunol. Rev, 2005 - interscience.wiley.com Summary: Type 1 diabetes (T1D) in both humans and nonobese diabetic (NOD) mice
is a T-cell-mediated autoimmune disease in which the insulin-producing
pancreatic islet β-cells are selectively eliminated. As a result, glucose ... Cited by 35 - Related articles - All 7 versions
H Beyan, LR Buckley, N Yousaf, M Londei, … - Diabetes/Metabolism Reviews - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 35 - Related articles - BL Direct - All 3 versions
B Fadeel, VE Kagan - Redox Report, 2003 - ingentaconnect.com However, the inflammatory reaction sometimes proceeds to an exacerbated or
chronic state and can thus, paradoxically, constitute a detrimental process that
is involved in numerous diseases, including rheumatoid arthritis, bronchial ... Cited by 31 - Related articles - BL Direct - All 3 versions
- ►nih.gov N Liadis, K Murakami, M Eweida, AR Elford, … - Molecular and Cellular Biology, 2005 - Am Soc Microbiol Type 1 diabetes mellitus is an autoimmune disease whereby antigen-specific
T-cells selectively destroy insulin-producing pancreatic ß cells. The activated
T cells first invade the islets, leading to insulitis. This is followed by ... Cited by 29 - Related articles - All 7 versions
BA O'Brien, X Geng, CH Orteu, Y Huang, M … - Journal of Autoimmunity, 2006 - Elsevier Deficiencies in apoptotic cell clearance have been linked to autoimmunity. Here
we examined the time-course of peritoneal macrophage phagocytosis of dying cells
following the direct injection of apoptotic thymocytes into the peritoneum ... Cited by 27 - Related articles - All 4 versions
