JB Choi, H Uchino, K Azuma, N Iwashita, Y … - Diabetologia, 2003 - Springer Aims/hypothesis. Bone marrow cells contain at least two distinct types of stem
cells which are haemato- poietic stem cells and mesenchymal stem cells. Both
cells have the ability to differentiate into a variety of cell types ... Cited by 134 - Related articles - BL Direct - All 3 versions
- ►cell.com SK Chakrabarti, RG Mirmira - Trends in Endocrinology & Metabolism, 2003 - Elsevier Transcription factors orchestrate intricate pathways of cellular growth and
differentiation by regulating the rate of transcription of an array of genes.
Genetic and biochemical studies have begun to unravel the complex cascade ... Cited by 66 - Related articles - All 12 versions
- ►jbc.org SK Chakrabarti, J Francis, SM Ziesmann, JC … - Journal of Biological Chemistry, 2003 - ASBMB Histone modifying enzymes contribute to the activation or inactivation of
transcription by ultimately catalyzing the unfolding or further compaction,
respectively, of chromatin structure. Actively transcribed genes are ... Cited by 60 - Related articles - BL Direct - All 5 versions
Y Kajimoto, H Kaneto - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2004 - interscience.wiley.com Abstract: Oxidative stress is produced under diabetic conditions and is likely
involved in progression of pancreatic β-cell dysfunction found in diabetes.
Possibly caused by low levels of antioxidant enzyme expressions, pancreatic ... Cited by 58 - Related articles - BL Direct - All 5 versions
L Ouziel-Yahalom, M Zalzman, L Anker-Kitai, S … - Biochemical and Biophysical Research …, 2006 - Elsevier Type 1 diabetes is caused by autoimmune destruction of the pancreatic islet
insulin-producing β cells. Insulin administration does not prevent long-term
complications of the disease, since the optimal insulin dosage is difficult ... Cited by 52 - Related articles - All 4 versions
- ►diabetesjournals.org H Kaneto, Y Nakatani, T Miyatsuka, T … - Diabetes, 2005 - Am Diabetes Assoc Diabetes is the most prevalent and serious metabolic disease, and the number of
diabetic patients worldwide is increasing. The reduction of insulin biosynthesis
in pancreatic β-cells is closely associated with the onset and progression ... Cited by 50 - Related articles - All 6 versions
H Kaneto, T Matsuoka, Y Nakatani, D … - Journal of Molecular Medicine, 2005 - Springer Page 1. J Mol Med (2005) 83: 429–439 DOI 10.1007/s00109-005-0640-x REVIEW Hideaki
Kaneto . Taka-aki Matsuoka . Yoshihisa Nakatani . Dan Kawamori . ... Cited by 46 - Related articles - All 3 versions
T Miyatsuka, H Kaneto, Y Kajimoto, S Hirota, … - Biochemical and Biophysical Research …, 2003 - Elsevier To date, the potency of pancreatic and duodenal homeobox gene 1 (PDX-1) in
inducing differentiation into insulin-producing cells has been demonstrated in
some cells and tissues. In order to carry out efficient screening of ... Cited by 46 - Related articles - All 6 versions
- ►alphamedpress.org O Karnieli, Y Izhar-Prato, S Bulvik, S Efrat - Stem Cells, 2007 - AlphaMed Press We have recently shown that stable expression of pancreatic duodenal homeobox 1
(PDX1), a transcription factor that plays key roles in pancreas development and
β-cell gene expression, in cultured human fetal liver cells activates a ... Cited by 39 - Related articles - BL Direct - All 6 versions
MF McCarty - Medical hypotheses, 2005 - Elsevier Recent prospective epidemiology links heavy coffee consumption to a substantial
reduction in risk for type 2 diabetes. Yet there is no evidence that coffee
improves insulin sensitivity and, at least in acute studies, caffeine has a ... Cited by 37 - Related articles - All 26 versions