- ►diabetesjournals.org M Cnop, N Welsh, JC Jonas, A Jörns, S Lenzen, DL … - Diabetes, 2005 - Am Diabetes Assoc Type 1 and type 2 diabetes are characterized by progressive β-cell failure. Apoptosis is probably
the main form of β-cell death in both forms of the disease. It has been suggested that the
mechanisms leading to nutrient- and ... Cited by 174 - Related articles - BL Direct - All 10 versions
- ►physiology.org MZ Khaldi, Y Guiot, P Gilon, JC Henquin, … - American Journal of …, 2004 - Am Physiological Soc Chronic hyperglycemia has been shown to induce either a lack of response or an increased sensitivity
to glucose in pancreatic -cells. We reinvestigated this controversial issue in a single experimental
model by culturing rat islets for 1 ... Cited by 29 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org N Kaiser, R Nesher, MY Donath, M Fraenkel, V Behar, … - Diabetes, 2005 - Am Diabetes Assoc Type 2 diabetes is characterized by insulin resistance and progressive ß-cell failure. Deficient
insulin secretion, with increased proportions of insulin precursor molecules, is a common feature of
type 2 diabetes; this could result ... Cited by 26 - Related articles - BL Direct - All 6 versions
JC Jonas, Y Guiot, J Rahier, JC Henquin - Diabetologia, 2003 - Springer Aim/hypothesis. Increased expression of haeme-oxyge- nase 1 (HO1) and other antioxidant enzymes
could im- prove pancreatic beta-cell survival under stressful condi- tions, including
hyperglycaemia. However, how hyper- ... Cited by 20 - Related articles - BL Direct - All 5 versions
- ►nih.gov I Quesada, MG Todorova, B Soria - Biophysical journal, 2006 - Elsevier Blood glucose homeostasis is mainly achieved by the coordinated function of pancreatic α-, β-, and
δ-cells, which secrete glucagon, insulin, and somatostatin, respectively. Each cell type responds
to glucose changes with different ... Cited by 18 - Related articles - BL Direct - All 7 versions
- ►physiology.org SM Katzman, MA Messerli, DT Barry, A … - American Journal of …, 2004 - Am Physiological Soc The cells within the intact islet of Langerhans function as a metabolic syncytium, secreting insulin
in a coordinated and oscillatory manner in response to external fuel. With increased glucose, the
oscillatory amplitude is enhanced, ... Cited by 7 - Related articles - BL Direct - All 4 versions
V Attali, M Parnes, Y Ariav, E Cerasi, N Kaiser, G … - Endocrinology, 2006 - Endocrine Soc Succinate stimulates insulin secretion and proinsulin biosynthesis. We studied the effects of
reduced nicotinamide adenine dinucleotide phosphate (NADPH)-modulating pathways on glucose- and
succinate-stimulated insulin ... Cited by 5 - Related articles - BL Direct - All 4 versions
S Hefetz, E Ziv, A Jörns, S Lenzen, E … - Diabetes/Metabolism … - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets. In
this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the ... Cited by 1 - Related articles - BL Direct - All 3 versions
J Zhang, R Luo, H Wu, S Wei, W Han, GD Li - Endocrinology, 2009 - Endocrine Soc Insulin secretion from β-cells is regulated by a complex signaling network. Our earlier study has
reported that Rac1 participates in glucose- and cAMP-induced insulin secretion probably via
maintaining a functional actin ... Related articles - All 3 versions
