WA Hsueh, CJ Lyon, MJ Quiñones - The American journal of medicine, 2004 - Elsevier There is increasing evidence of a parallel progression between insulin resistance and endothelial
dysfunction, suggesting a close association between insulin action and the endothelium. Numerous
studies have demonstrated that endothelial dysfunction occurs early in the ... Cited by 151 - Related articles - All 9 versions
MA Vincent, M Montagnani, MJ Quon - Current Diabetes Reports, 2003 - Springer Insulin has important vascular actions that regulate blood flow, in addition to its classical actions
to coordinate glu- cose homeostasis. Insulin-stimulated production of nitric oxide in vascular
endothelium results in capillary recruit- ment and vasodilation that diverts and increases ... Cited by 90 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org H Chen, G Sullivan, MJ Quon - Diabetes, 2005 - Am Diabetes Assoc The quantitative insulin-sensitivity check index (QUICKI) has an excellent linear correlation with
the glucose clamp index of insulin sensitivity (SI Clamp ) that is better than that of many other
surrogate indexes. However, correlation between a surrogate and reference standard ... Cited by 70 - Related articles - All 5 versions
- ►ahajournals.org M Yano, T Matsumura, T Senokuchi, N Ishii, Y … - Circulation …, 2007 - Am Heart Assoc Both statins and peroxisome proliferator-activated receptor (PPAR) ligands have been reported
to protect against the progression of atherosclerosis. In the present study, we investigated the
effects of statins on PPAR activation in macrophages. Statins increased PPAR activity, ... Cited by 45 - Related articles - All 4 versions
- ►physiology.org H Chen, RJ Karne, G Hall, U Campia, JA … - American Journal of …, 2006 - Am Physiological Soc Endothelial dysfunction is a hallmark of Type 2 diabetes related to hyperglycemia and oxidative
stress. Nitric oxide-dependent vasodilator actions of insulin may augment glucose disposal. Thus
endothelial dysfunction may worsen insulin resistance. Intra-arterial administration of ... Cited by 44 - Related articles - BL Direct - All 4 versions
- ►jlr.org J Pihlajamaki, H Gylling, TA Miettinen, M Laakso - The Journal of Lipid …, 2004 - ASBMB Type 2 diabetes has been associated with high synthesis and low absorption of cholesterol independent
of weight, indicating that insulin resistance may be a link between glucose and cholesterol
metabolism. Therefore, we investigated the relationship of serum cholesterol precursors, ... Cited by 46 - Related articles - BL Direct - All 4 versions
- ►fasebj.org FR DANESH, YS KANWAR - The FASEB Journal, 2004 - FASEB 3-Hydroxy-3-methyl-glutaryl CoA (HMG-CoA) reductase inhibitors or statins are competitive inhibitors
of the rate-limiting enzyme in cholesterol biosynthesis. Several large landmark clinical studies
have shown a marked reduction of cardiovascular mortality and morbidity in patients ... Cited by 41 - Related articles - BL Direct - All 5 versions
- ►nih.gov M Chakir, GE Plante - Prostaglandins, Leukotrienes & Essential Fatty Acids, 1996 - Elsevier In the present study, we examined the pattern of Evan's blue (EB) extravasation over time and
we verified the effect of two inhibitors of aldose reductase (sorbinil and ARI 509) as well as
aminoguanidine, which modulate nitric oxide (NO) production, on streptozotocin-induced ... Cited by 35 - Related articles - BL Direct - All 12 versions
S Huptas, HC Geiss, C Otto, KG Parhofer - The American journal of cardiology, 2006 - Elsevier Large interventional studies have shown that statins may reduce the incidence of type 2 diabetes
mellitus. However, it is uncertain whether short-term statin therapy can affect insulin sensitivity
in patients with the metabolic syndrome. We evaluated the effect of atorvastatin (10 ... Cited by 34 - Related articles - All 10 versions
V Wong, L Stavar, L Szeto, K Uffelman, CH Wang, IG … - Atherosclerosis, 2006 - Elsevier In vivo studies of insulin sensitization were performed in chow fed Zucker lean and fatty rats treated
with atorvastatin 50 mg/kg/day (ATORVA_50) and results were compared to Zucker lean and
fatty rats treated with drug vehicle only (CONT). Additional Zucker lean rats were treated ... Cited by 25 - Related articles - All 13 versions
