- ►physiology.org MJ MacDonald, LA Fahien, LJ Brown, NM … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc The importance of mitochondrial biosynthesis in stimulus secretion coupling in
the insulin-producing -cell probably equals that of ATP production. In
glucose-induced insulin secretion, the rate of pyruvate carboxylation is ... Cited by 60 - Related articles - All 4 versions
- ►jbc.org GA Martens, Y Cai, S Hinke, G Stange, M Van … - Journal of Biological Chemistry, 2005 - ASBMB High rates of glucose metabolism and mitochondrial electron transport have been
associated with increased mitochondrial production of reactive oxygen species
(ROS). This mechanism was also proposed as a possible cause for dysfunction ... Cited by 32 - Related articles - All 6 versions
- ►diabetesjournals.org [PDF] M Maeda, I Yamamoto, M Fukuda, M Nishida, J … - Diabetes Care, 2003 - Am Diabetes Assoc Cross-sectional studies of the com- bined intima-media wall thickness (IMT) of
the carotid arteries per- formed in type 1 diabetic patients show partly
contradictory results with regard to variables that are associated with the ... Cited by 27 - Related articles - BL Direct - All 5 versions
- ►shouxi.net C Guay, SR Madiraju, A Aumais, E Joly, M … - Journal of Biological Chemistry, 2007 - ASBMB In pancreatic β-cells, metabolic coupling factors generated during glucose
metabolism and pyruvate cycling through anaplerosis/cataplerosis processes
contribute to the regulation of insulin secretion. Pyruvate/citrate cycling ... Cited by 25 - Related articles - All 4 versions
- ►diabetesjournals.org [PDF] AE Brynes, JL Lee, RE Brighton, AR Leeds, A … - Diabetes Care, 2003 - Am Diabetes Assoc Cross-sectional studies of the com- bined intima-media wall thickness (IMT) of
the carotid arteries per- formed in type 1 diabetic patients show partly
contradictory results with regard to variables that are associated with the ... Cited by 17 - Related articles - BL Direct - All 6 versions
M Fex, MD Nitert, N Wierup, F Sundler, C Ling … - Diabetologia, 2007 - Springer Abstract Aim/hypothesis Hyperinsulinaemia maintains euglycaemia in
insulin-resistant states. The precise cellular mechanisms by which the beta
cells adapt are still unresolved. A peripherally derived cue, such as ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►jbc.org MJ MacDonald, AD Smith III, NM Hasan, G … - Journal of Biological Chemistry, 2007 - ASBMB The mitochondria of pancreatic beta cells are believed to convert insulin
secretagogues into products that are translocated to the cytosol where they
participate in insulin secretion. We studied the hypothesis that short ... Cited by 15 - Related articles - All 5 versions
A Farret, M Vignaud, S Dietz, J Vignon, P … - Diabetes, 2004 - Am Diabetes Assoc Purine nucleotides and their analogs increase insulin secretion through
activation of pancreatic β-cell P2Y receptors. The present study aimed at
determining the role of glucose metabolism in the response to P2Y agonists ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►jbc.org MJ MacDonald - Journal of Biological Chemistry, 2007 - ASBMB Insulin secretion by the beta cell depends on anaplerosis in which insulin
secretagogues are metabolized by mitochondria into molecules that are most
likely exported to the extramitochondrial space where they have signaling ... Cited by 13 - Related articles - All 7 versions
NE Simpson, N Khokhlova, JA Oca-Cossio, I … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 1338–1348 DOI 10.1007/s00125-006-0216-5 ARTICLE
NE Simpson . N. Khokhlova . JA Oca-Cossio . I. Constantinidis ... Cited by 11 - Related articles - BL Direct - All 3 versions