GD Tan, BA Fielding, JM Currie, SM … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: We investigated the effects of rosiglitazone on NEFA
and triglyceride metabolism in type 2 diabetes. Methods: In a double-blind,
placebo-con- trolled, cross-over study of rosiglitazone in diet-treated ... Cited by 85 - Related articles - All 2 versions
A Natali, E Ferrannini - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: Insulin resistance, which manifests itself as
endogenous glucose overproduction and reduced insulin-mediated glucose uptake,
is a core defect in type 2 diabetes. Metformin and the peroxisome ... Cited by 56 - Related articles - BL Direct - All 3 versions
J ŽDYCHOVÁ, R Komers - Physiol. Res, 2005 - biomed.cas.cz Summary In addition to a number of deleterious effects on cellular integrity and
functions, diabetic metabolic milieu has been implicated in a rapidly growing
number of alterations in signal transduction. In this review we focus on ... Cited by 42 - Related articles - View as HTML - All 5 versions
AM Valverde, M Benito, M Lorenzo… - Acta Physiologica Scandinavica, 2005 - med.uio.no Abstract Type 2 diabetes mellitus is a complex metabolic disease that occurs
when insulin secretion can no longer compensate insulin resistance in peripheral
tissues. At the molecular level, insulin resistance correlates with ... Cited by 41 - Related articles - View as HTML - All 4 versions
- ►endojournals.org CY Lin, T Gurlo, L Haataja, WA Hsueh, PC … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Methods and Results: Vehicle or h-IAPP was applied to human islets with or
without RSG (10 and 50 µM) for 48 h. A 2-fold increase in the number of
terminal deoxynucleotidyl transferase-mediated deoxy-UTP nick end labeling- ... Cited by 36 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org HKR Karlsson, K Hällsten, M Björnholm, H … - Diabetes, 2005 - Am Diabetes Assoc The effect of metformin or rosiglitazone monotherapy versus placebo on insulin
signaling and gene expression in skeletal muscle of patients with newly
diagnosed type 2 diabetes was determined. A euglycemic-hyperinsulinemic ... Cited by 34 - Related articles - All 6 versions
- ►physiology.org Y Ye, Y Lin, S Atar, MH Huang, JR Perez-Polo … - American Journal of Physiology- Heart and Circulatory …, 2006 - Am Physiological Soc We assessed 1) whether pretreatment before ischemia with pioglitazone (Pio)
limits infarct size (IS) and whether this protective effect is due to nitric
oxide synthase (NOS) and/or prostaglandin production, as has been shown for ... Cited by 35 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] G Jiang, Q Dallas-Yang, S Biswas, Z Li, BB … - Biochemical Journal, 2004 - pubmedcentral.nih.gov Biochem. J. (2004) 377, 339–346 (Printed in Great Britain) ... Rosiglitazone,
an agonist of peroxisome-proliferator-activated receptor γ ... (PPARγ),
decreases inhibitory serine phosphorylation of IRS1 in vitro Cited by 26 - Related articles - BL Direct - All 10 versions
- ►physiology.org AR Gosmanov, GE Umpierrez, AH Karabell, … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Although a pharmacological dose of insulin produces a dramatic increase in
phosphorylation and activity of Akt isoforms 1 and 2 in mammalian skeletal
muscle, few studies have examined the effect of physiological ... Cited by 24 - Related articles - All 4 versions
- ►endocrinology-journals.org M Schutt, J Zhou, M Meier, HH Klein - Journal of Endocrinology, 2004 - Soc Endocrinology The mechanism by which chronic treatment with HIV (human immunodeficiency
virus)-1 protease inhibitors leads to a deterioration of glucose metabolism
appears to involve insulin resistance, and may also involve impaired ... Cited by 24 - Related articles - All 4 versions
