B Kemp, D Stapleton, D Campbell, Z Chen … - Biochemical Society …, 2003 - bst.portlandpress.com Abbreviations used: AMPK, AMP-activated protein kinase; AMPKK, AMPK kinase; HMGR,
3-hydroxy-3-methylglutaryl-CoA reductase; GBD, glycogen-binding domain; AICAR,
5-amino-4-imidazolecarboxamide ... Cited by 216 - Related articles - Cached - BL Direct - All 9 versions
GA Rutter, GDS Xavier, I Leclerc - Biochemical Journal, 2003 - pubmedcentral.nih.gov AMPK (5 -AMP-activated protein kinase) is emerging as a meta- bolic master switch, by which cells in
both mammals and lower organisms sense and decode changes in energy status. Changes in AMPK activity
have been shown to regulate glucose ... Cited by 141 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org HA Koistinen, D Galuska, AV Chibalin, J Yang, JR … - Diabetes, 2003 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) activation by AICAR (5-amino-imidazole carboxamide riboside) is
correlated with increased glucose transport in rodent skeletal muscle via an insulin-independent
pathway. We determined in vitro ... Cited by 97 - Related articles - BL Direct - All 7 versions
X Yu, S McCorkle, M Wang, Y Lee, J Li, AK Saha, RH … - Diabetologia, 2004 - Springer Aims/hypothesis. Leptin has been shown to activate AMP-activated protein kinase (AMPK), an enzyme
that regulates the activities of key enzymes of lipid synthesis and metabolism. We assess here (i)
whether AMPK activity is diminished ... Cited by 56 - Related articles - All 3 versions
- ►diabetesjournals.org A Sriwijitkamol, DK Coletta, E Wajcberg, GB Balbontin, … - Diabetes, 2007 - Am Diabetes Assoc Activation of AMP-activated protein kinase (AMPK) by exercise induces several cellular processes in
muscle. Exercise activation of AMPK is unaffected in lean (BMI ∼25 kg/m 2 ) subjects with type 2
diabetes. However, most type 2 ... Cited by 51 - Related articles - BL Direct - All 4 versions
- ►endojournals.org L Al-Khalili, K Bouzakri, S Glund, F Lonnqvist, … - Molecular …, 2006 - Endocrine Soc We identified signaling pathways by which IL-6 regulates skeletal muscle differentiation and
metabolism. Primary human skeletal muscle cells were exposed to IL-6 (25 ng/ml either acutely or for
several days), and small ... Cited by 49 - Related articles - BL Direct - All 6 versions
- ►physiology.org A Sriwijitkamol, JL Ivy, C Christ-Roberts, … - American Journal of …, 2006 - Am Physiological Soc AMPK is a key regulator of fat and carbohydrate metabolism. It has been postulated that defects in
AMPK signaling could be responsible for some of the metabolic abnormalities of type 2 diabetes. In
this study, we examined whether ... Cited by 43 - Related articles - BL Direct - All 3 versions
- ►fasebj.org BR Barnes, S Glund, YC Long, G Hjalm, L Andersson, … - The FASEB journal, 2005 - FASEB 5'-AMP-activated protein kinase (AMPK) activity is increased during exercise in an intensity- and
glycogen-dependent manner. We previously reported that a mutation in the AMPK 3 subunit (Prkag3 225Q
) increases AMPK activity and ... Cited by 32 - Related articles - All 3 versions
J Yang, GD Holman - Journal of Biological Chemistry, 2005 - ASBMB Stimulations of glucose transport produced by insulin action, contraction, or through a change in
cell energy status are mediated by separate signaling pathways. These are the wortmannin-sensitive
phosphatidylinositol 3-kinase ... Cited by 32 - Related articles - All 7 versions
N Musi, H Yu, L Goodyear - Biochemical Society Transactions, 2003 - bst.portlandpress.com Physical exercise increases muscle glucose uptake, enhances insulin sensitivity and leads to fatty
acid oxidation in muscle. The AMP-activated protein kinase (AMPK) is an energy-sensing enzyme that
is strongly activated during muscle ... Cited by 29 - Related articles - Cached - BL Direct - All 8 versions
