- ►rh.dk [PDF] LL Baggio, DJ Drucker - Gastroenterology, 2007 - Elsevier This review focuses on the mechanisms regulating the synthesis, secretion, biological
actions, and therapeutic relevance of the incretin peptides glucose-dependent insulinotropic
polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). The published literature was ... Cited by 179 - Related articles - All 25 versions
- ►stanford.edu [PDF] MK Badman, JS Flier - Science, 2005 - sciencemag.org In addition to digesting and assimilating nutrients, the intestine and associated visceral organs
play a key sensing and signaling role in the physiology of energy homeostasis. The gut, the pancreatic
islets of Langerhans, elements in the portal vasculature, and even visceral adipose tissue ... Cited by 162 - Related articles - All 14 versions
- ►nih.gov DE Cummings, J Overduin - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig Despite substantial fluctuations in daily food intake, animals maintain a remarkably stable body
weight, because overall caloric ingestion and expenditure are exquisitely matched over long
periods of time, through the process of energy homeostasis. The brain receives hormonal, ... Cited by 152 - Related articles - BL Direct - All 10 versions
EMD Nielsen, L Hansen, B Carstensen, SM Echwald, T … - Diabetes, 2003 - Am Diabetes Assoc The E23K polymorphism of the pancreatic β-cell ATP-sensitive K + (K ATP ) channel subunit
Kir6.2 (KCNJ11) is associated with type 2 diabetes in whites, and a recent in vitro study of the
E23K variant suggests that the association to diabetes might be explained by a slight ... Cited by 147 - Related articles - BL Direct - All 5 versions
FM Gribble, F Reimann - Diabetologia, 2003 - Springer Hypoglycaemic agents such as sulphonylureas and the newer group of “glinides” stimulate insulin
secretion by closing ATP-sensitive potassium (K ATP ) channels in pancreatic beta cells, but
have varying cross-reac- tivity with related channels in extrapancreatic tissues such as ... Cited by 107 - Related articles - BL Direct - All 3 versions
CF Deacon - Regulatory peptides, 2005 - Elsevier The incretin hormones, glucose-dependent insulinotropic peptide (GIP) and glucagon-like
peptide-1 (GLP-1) are secreted from endocrine cells located in the intestinal mucosa, and act
to enhance meal-induced insulin secretion. GIP and GLP-1 concentrations in the plasma ... Cited by 70 - Related articles - All 6 versions
- ►physiology.org … , O Carlson, S Michopoulos, ME Doyle, M … - American Journal of …, 2006 - Am Physiological Soc Among the products of enteroendocrine cells are the incretins glucagon-like peptide-1
(GLP-1, secreted by L cells) and glucose-dependent insulinotropic peptide (GIP, secreted by
K cells). These are key modulators of insulin secretion, glucose homeostasis, and gastric ... Cited by 52 - Related articles - BL Direct - All 4 versions
- ►hivinfosource.org [PDF] MJ Riedel, P Boora, D Steckley, G de Vries, PE Light - Diabetes, 2003 - Am Diabetes Assoc The commonly occurring E23K and I337V Kir6.2 polymorphisms in the ATP-sensitive potassium
(K ATP ) channel are more frequent in Caucasian type 2 diabetic populations. However, the underlying
cellular mechanisms contributing to the pathogenesis of type 2 diabetes remain ... Cited by 51 - Related articles - BL Direct - All 25 versions
PL Brubaker, Y Anini - Canadian journal of physiology and …, 2003 - article.pubs.nrc-cnrc.gc.ca Abstract: The proglucagon-derived peptide family consists of three highly related peptides, glucagon
and the glucagon-like peptides GLP-1 and GLP-2. Although the biological activity of glucagon
as a counter-regulatory hormone has been known for almost a century, studies conducted ... Cited by 49 - Related articles - BL Direct - All 9 versions
