- ►diabetes.com.au [PDF] KGMM Alberti, P Zimmet, J Shaw - The Lancet, 2005 - Elsevier The ultimate importance of metabolic syndrome is that it helps identify individuals at high risk
of both type 2 diabetes and cardiovascular disease (CVD). Several expert groups have therefore
attempted to produce diagnostic criteria. The first attempt was by a WHO diabetes group ... Cited by 2178 - Related articles - BL Direct - All 11 versions
- ►ahajournals.org SM Grundy, JI Cleeman, SR Daniels, KA Donato, RH … - Circulation, 2005 - Am Heart Assoc The metabolic syndrome is a constellation of interrelated risk factors of metabolic origin—metabolic
risk factors—that appear to directly promote the development of atherosclerotic cardiovascular
disease (ASCVD). 1 Patients with the metabolic syndrome also are at increased risk for ... Cited by 2071 - Related articles - BL Direct - All 11 versions
- ►drclaudiaanrig.com [PDF] RH Eckel, SM Grundy, PZ Zimmet - The Lancet, 2005 - Elsevier The metabolic syndrome is a common metabolic disorder that results from the increasing prevalence
of obesity. The disorder is defined in various ways, but in the near future a new definition(s) will
be applicable worldwide. The pathophysiology seems to be largely attributable to insulin ... Cited by 1569 - Related articles - All 41 versions
- ►hopkinsmedicine.org [PDF] SE Kahn, SM Haffner, MA Heise, WH Herman, … - New England Journal …, 2006 - content.nejm.org From the Veterans Affairs Puget Sound Health Care System and University of Washington, Seattle
(SEK); University of Texas Health Science Center at San An tonio, San Antonio (SMH); GlaxoSmith
Kline, King of Prussia, PA (MAH, BGK, MCO), and Harlow, Essex, United King dom (NPJ); ... Cited by 781 - Related articles - BL Direct - All 30 versions
JS Torgerson, J Hauptman, MN Boldrin, L Sjöström - Diabetes Care, 2004 - Am Diabetes Assoc RESULTS—Of orlistat-treated patients, 52% completed treatment compared with 34% of placebo
recipients (P < 0.0001). After 4 years' treatment, the cumulative incidence of diabetes was
9.0% with placebo and 6.2% with orlistat, corresponding to a risk reduction of 37.3% (P = ... Cited by 737 - Related articles - BL Direct - All 10 versions
- ►stuba.sk [PDF] M Valko, D Leibfritz, J Moncol, MTD Cronin, M … - International Journal of …, 2007 - Elsevier Reactive oxygen species (ROS) and reactive nitrogen species (RNS, eg nitric oxide, NO ) are
well recognised for playing a dual role as both deleterious and beneficial species. ROS and
RNS are normally generated by tightly regulated enzymes, such as NO synthase (NOS) ... Cited by 695 - Related articles - All 9 versions
SE Kahn - Diabetologia, 2003 - Springer The relative contributions of insulin resistance and be- ta-cell dysfunction to the pathophysiology
of Type 2 diabetes have been debated extensively. The concept that a feedback loop governs
the interaction of the in- sulin-sensitive tissues and the beta cell as well as the elucidation ... Cited by 517 - Related articles - BL Direct - All 6 versions
- ►harvard.edu [PDF] M Stumvoll, BJ Goldstein, TW van Haeften - The Lancet, 2005 - Elsevier Type 2 diabetes mellitus has become an epidemic, and virtually no physician is without patients
who have the disease. Whereas insulin insensitivity is an early phenomenon partly related to
obesity, pancreas β-cell function declines gradually over time already before the onset of ... Cited by 441 - Related articles - All 17 versions
C Lorenzo, M Okoloise, K Williams, MP Stern, SM … - Diabetes Care, 2003 - Am Diabetes Assoc RESULTS—IGT and the NCEP definition had higher sensitivity than the modified WHO definition
(51.9, 52.8, and 42.8%, respectively). IGT had a higher positive predictive value than the NCEP
and modified WHO definitions (43.0, 30.8, and 30.4%, respectively). The combination of ... Cited by 397 - Related articles - BL Direct - All 7 versions
- ►endojournals.org CJ Lyon, RE Law, WA Hsueh - Endocrinology, 2003 - Endocrine Soc Adipose tissue is a dynamic endocrine organ that secretes a number of factors that are increasingly
recognized to contribute to systemic and vascular inflammation. Several of these factors, collectively
referred to as adipokines, have now been shown regulate, directly or indirectly, a number ... Cited by 395 - Related articles - BL Direct - All 4 versions
