- ►kfshrc.edu.sa [PDF] LE Mitchell, NS Adzick, J Melchionne, PS … - The Lancet, 2004 - Elsevier Spina bifida results from failure of fusion of the caudal neural tube, and is
one of the most common malformations of human structure. The causes of this
disorder are heterogeneous and include chromosome abnormalities, single ... Cited by 108 - Related articles - All 10 versions
- ►diabetesjournals.org P Wentzel, A Ejdesjö, UJ Eriksson - Diabetes, 2003 - Am Diabetes Assoc The aim of the present study was to investigate whether diabetic embryopathy may
be associated with the inhibition of glyceraldehyde-3-phosphate dehydrogenase
(GAPDH) resulting from an excess of reactive oxygen species (ROS) in the ... Cited by 36 - Related articles - BL Direct - All 5 versions
MR Loeken - American Journal of Medical Genetics Part C Seminars …, 2005 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 32 - Related articles - All 4 versions
- ►physiology.org R Li, M Chase, SK Jung, PJS Smith, MR … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc We have shown that neural tube defects (NTD) in a mouse model of diabetic
embryopathy are associated with deficient expression of Pax3, a gene required
for neural tube closure. Hyperglycemia-induced oxidative stress is ... Cited by 30 - Related articles - BL Direct - All 9 versions
- ►physiology.org [PDF] S Chu, HG Bohlen - American Journal of Physiology- Renal Physiology, 2004 - Am Physiological Soc 52 articles, 25 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/287/3/F384#BIBL ... 6 other
HighWire hosted articles, the first 5 are: This article has been cited by Cited by 24 - Related articles - BL Direct - All 7 versions
M Horal, Z Zhang, R Stanton, A Virkamaeki, … - Birth Defects Research Part A: Clinical and Molecular …, 2004 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 24 - Related articles - All 4 versions
MR Loeken - Journal of Maternal-Fetal and Neonatal Medicine, 2004 - informahealthcare.com Maternal diabetes significantly increases the risk for birth defects. Studies
using animal models indicate that oxidative stress may play a causative role.
Oxidative stress can result from exposure to certain drugs, ionizing ... Cited by 23 - Related articles - BL Direct - All 6 versions
J Fu, SSW Tay, EA Ling, ST Dheen - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: Maternal diabetes induces neural tube defects during
embryogenesis. Since the neural tube is derived from neural stem cells (NSCs),
it is hypothesised that in diabetic pregnancy neural tube defects result ... Cited by 22 - Related articles - BL Direct - All 4 versions
A Jawerbaum, E Gonzalez - Current pharmaceutical design, 2005 - ingentaconnect.com 14 PGJ 2 , involved in signalling and developmental pathways), and by enhancing
the generation of nitric oxide (a mediator of many cell functions including
apoptotic cell death). In maternal diabetes all of these abnormalities are ... Cited by 20 - Related articles - All 3 versions
JF Di Mari, RC Mifflin, DW Powell - Gastroenterology, 2005 - Elsevier Externally triggered signaling pathways allow cells to adapt to their
environment through diverse cellular responses. In a given milieu, depending on
cell and stimulus specificity, the activation of these pathways may induce ... Cited by 16 - Related articles - All 9 versions
