- ►endojournals.org BL Wajchenberg - Endocrine reviews, 2007 - Endocrine Soc There is a progressive deterioration in ß-cell function and mass in type 2
diabetics. It was found that islet function was about 50% of normal at the time
of diagnosis, and a reduction in ß-cell mass of about 60% was shown at ... Cited by 100 - Related articles - BL Direct - All 7 versions
GM Steil, AE Panteleon, K Rebrin - Advanced drug delivery reviews, 2004 - Elsevier The development of an artificial pancreas for the treatment of insulin-dependent
diabetes is a highly desired endeavor for patients, physicians, scientists, and
engineers. Historical algorithms and recent progress in research and ... Cited by 92 - Related articles - All 4 versions
M Uusitupa, V Lindi, A Louheranta, T Salopuro … - Diabetes, 2003 - Am Diabetes Assoc Lifestyle interventions reduce the incidence of type 2 diabetes among
individuals with impaired glucose tolerance (IGT). However, it is unknown
whether this is due to improved insulin sensitivity or insulin secretion. ... Cited by 80 - Related articles - BL Direct - All 8 versions
- ►oxfordjournals.org F Ashcroft, P Rorsman - Human molecular genetics, 2004 - Oxford Univ Press Type 2 diabetes mellitus is a serious metabolic disease that afflicts around 5%
of the population in Western societies and over 150 million people worldwide. It
is characterized by elevation of the blood glucose concentration, usually ... Cited by 70 - Related articles - All 5 versions
- ►mcponline.org JC Sanchez, V Converset, A Nolan, G Schmid, … - Molecular & Cellular Proteomics, 2002 - ASBMB The insulin sensitizer drug, rosiglitazone, has been shown to have a protective
effect on pancreatic islet cell structure and function in animal models of type
2 diabetes. The identification of new molecular targets associated both ... Cited by 52 - Related articles - BL Direct - All 3 versions
IF Godsland, JAR Jeffs, DG Johnston - Diabetologia, 2004 - Springer Aims/hypothesis. Our aim was to define the level of glycaemia at which
pancreatic insulin secretion, particularly first-phase insulin release, begins
to decline. Methods. Plasma glucose and insulin concentrations were ... Cited by 51 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org M Hagen, J Hjelmesaeth, T Jenssen, L … - Nephrology Dialysis Transplantation, 2003 - ERA-EDTA Results. The proportion of recipients with normal glucose tolerance (NGT) rose
from 46% (baseline) to 65% (follow-up) (P = 0.008), and median fasting and 2-h
serum glucose were reduced by 0.7 mmol/l (P < 0.001) and 1.3 mmol/l (P = ... Cited by 41 - Related articles - BL Direct - All 5 versions
- ►shouxi.net JC Henquin, M Nenquin, P Stiernet, B Ahren - Diabetes, 2006 - Am Diabetes Assoc The mechanisms underlying biphasic insulin secretion have not been completely
elucidated. We compared the pattern of plasma insulin changes during
hyperglycemic clamps in mice to that of glucose-induced insulin secretion ... Cited by 36 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org H Suzuki, M Fukushima, M Usami, M Ikeda, A … - Diabetes Care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—We conducted cross-sectional analysis of 231
Japanese men aged 20–70 years. The subjects were classified into the following
three groups, based on the results of a 75-g oral glucose tolerance test ... Cited by 31 - Related articles - BL Direct - All 5 versions
- ►endojournals.org MJ De Blasio, KL Gatford, IC McMillen, JS … - Endocrinology, 2007 - Endocrine Soc Most children who are short or light at birth due to intrauterine growth
restriction (IUGR) exhibit accelerated growth in infancy, termed "catch-up"
growth, which together with IUGR, predicts increased risk of type 2 ... Cited by 27 - Related articles - BL Direct - All 5 versions
