- ►cell.com J Rizo, X Chen, D Araç - Trends in cell biology, 2006 - Elsevier SNARE proteins and synaptotagmin are key components of the complex machinery
that controls Ca 2+ -triggered neurotransmitter release but their mechanisms of
action are under debate. Recent research has shed light on which ... Cited by 98 - Related articles - All 9 versions
- ►jneurosci.org R Fernandez-Chacon, OH Shin, A … - Journal of Neuroscience, 2002 - Soc Neuroscience Synaptotagmin 1, a Ca 2+ sensor for fast synaptic vesicle exocytosis, contains
two C 2 domains that form Ca 2+ -dependent complexes with phospholipids. To
examine the functional importance of Ca 2+ binding to the C 2 A domain of ... Cited by 65 - Related articles - BL Direct - All 6 versions
D Araç, X Chen, HA Khant, J Ubach, SJ … - Nature structural & molecular biology, 2006 - nature.com 1 Departments of Biochemistry and Pharmacology, University of Texas Southwestern
Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA. ... 2
National Center for Macromolecular Imaging, Verna and Marrs McLean ... Cited by 55 - Related articles - BL Direct - All 6 versions
OH Shin, J Rizo, TC Südhof - Nature neuroscience, 2002 - nature.com Ca 2+ -triggered dense-core vesicle exocytosis in PC12 cells does not require
vesicular synaptotagmins 1 and 2, but may use plasma membrane synaptotagmins 3
and 7 as Ca 2+ sensors. In support of this hypothesis, C 2 domains from the ... Cited by 52 - Related articles - BL Direct - All 5 versions
- ►nih.gov JS Rhee, LY Li, OH Shin, JC Rah, J Rizo, TC … - Proceedings of the National Academy of Sciences, 2005 - National Acad Sciences Synaptotagmin 1 likely acts as a Ca 2+ sensor in neurotransmitter release by Ca
2+ -binding to its two C2 domains. This notion was strongly supported by the
observation that a mutation in the C2A domain causes parallel decreases in ... Cited by 32 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org EP Kwan, L Xie, L Sheu, CJ Nolan, M Prentki, … - Diabetes, 2006 - Am Diabetes Assoc Munc13-1 is a diacylglycerol (DAG) receptor that is essential for synaptic
vesicle priming. We recently showed that Munc13-1 is expressed in rodent and
human islet β-cells and that its levels are reduced in islets of type 2 ... Cited by 21 - Related articles - All 5 versions
AL Lomize, ID Pogozheva, MA Lomize, HI … - BMC Structural Biology, 2007 - biomedcentral.com We report the first large-scale computational study of monotopic/peripheral
proteins with known 3D structures. The optimal translational and rotational
positions of 476 proteins are determined by minimizing energy of protein ... Cited by 10 - Related articles - Cached - All 10 versions
CT Shearn, FA Norris - Biochemical and Biophysical Research …, 2007 - Elsevier Inositol polyphosphate 4 phosphatases (IP4Ps) are enzymes involved in the
regulation of phosphoinositide 3-kinase lipid signaling. They catalyze the
hydrolysis of the 4-position phosphate from phosphatidylinositol 3,4- ... Cited by 2 - Related articles - All 5 versions
HE Yuhong, LI Xianghui, W Fu, XUE Yi, SUI … - Chinese Science Bulletin, 2003 - scichina.com HE Yuhong, LI Xianghui, WANG Fu, XUE Yi & SUI Senfang Department of Biological
Sciences & Biotechnology, State Key Labo- ratory of Biomembrane, Tsinghua
University, Beijing 100084, China Correspondence should be addressed to Sui ... Related articles - View as HTML - All 3 versions