- ►oxfordjournals.org F Ashcroft, P Rorsman - Human molecular genetics, 2004 - Oxford Univ Press Type 2 diabetes mellitus is a serious metabolic disease that afflicts around 5% of the population
in Western societies and over 150 million people worldwide. It is characterized by elevation of
the blood glucose concentration, usually presents in middle age, and is exacerbated by ... Cited by 70 - Related articles - All 5 versions
JC Henquin, M Nenquin, P Stiernet, B Ahren - Diabetes, 2006 - Am Diabetes Assoc The mechanisms underlying biphasic insulin secretion have not been completely
elucidated. We compared the pattern of plasma insulin changes during hyperglycemic clamps
in mice to that of glucose-induced insulin secretion and cytosolic calcium concentration ... Cited by 36 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org NN Rudovich, HJ Rochlitz, AFH Pfeiffer - Diabetes, 2004 - Am Diabetes Assoc Our objective was to study whether young first-degree relatives of patients with type 2 diabetes
(FDRs) have altered insulin secretion and insulin clearance in response to gastric inhibitory polypeptide
(GIP) in combination with glucose and arginine. A hyperglycemic clamp (11.1 mmol/l for ... Cited by 29 - Related articles - BL Direct - All 4 versions
E Watson, S Hahm, TM Mizuno, J Windsor, C … - Endocrinology, 2005 - Endocrine Soc Targeted deletion of the gene encoding the neuronal and endocrine secreted peptide precursor
called VGF (nonacronymic) produces a lean, hypermetabolic, hyperactive mouse. Because VGF
mutant mice are resistant to specific forms of diet-, lesion-, and genetically induced ... Cited by 12 - Related articles - BL Direct - All 6 versions
WC Hsueh, KD Silver, TI Pollin, CJ Bell, JR O'Connell, … - Diabetes, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—We conducted a series of genetic analyses, including
genome-wide and fine-mapping linkage studies, based on insulin levels measured during an
oral glucose tolerance test (OGTT) in 552 nondiabetic participants in the Amish Family ... Cited by 4 - Related articles - BL Direct - All 8 versions
M Meurer, M Stumvoll, RM Szeimies - Der Hautarzt, 2004 - Springer Diabetes mellitus ist die häufigste Stoff- wechselerkrankung,deren klinische Hauptmanifestation
die Hyperglykämie ist.In Deutschland leiden knapp 5Mio. Menschen an dieser Erkrankung
(Präva- lenz von 6%) und in der Gruppe der über 50-Jährigen liegt die Prävalenz bei ... Cited by 2 - Related articles - All 3 versions
- ►spendocrinologia.org.pe [PDF] H Staiger, F Machicao, A Fritsche, HU Haring - Endocrine Reviews, 2009 - Endocrine Soc Type 2 diabetes mellitus is a complex metabolic disease that is caused by insulin resistance
and β-cell dysfunction. Furthermore, type 2 diabetes has an evident genetic component and
represents a polygenic disease. During the last decade, considerable progress was ... Related articles - All 4 versions
- ►tweelingenregister.org [PDF] AMC Simonis-Bik, EMW Eekhoff, MHM de Moor, MHH … - Diabetologia - Springer Abstract Aims/hypothesis The aim of the present study was to estimate the heritability of the beta
cell insulin response to glucose and to glucose combined with glucagon-like peptide-1
(GLP-1) or with GLP-1 plus arginine. Methods This was a twin-family study that included ... Related articles - All 3 versions
- ►uni-tuebingen.de [PDF] Ä Direktor, A Nieß - deposit.ddb.de 3.2.2 Waist-to-Hip Ratio (WHR)................................................................ 34 ... 3.6.5 Ermittlung der
Individuell Anaeroben Schwelle (IAS)....................... 48 ... 4.5 Zusammenhang zwischen Leistung
an der IAS und VO2max bei ... Personen mit normaler und gestörter Glukosetoleranz........ ... Related articles - All 3 versions