- ►diabetesjournals.org GG Holz - Diabetes, 2004 - Am Diabetes Assoc Recently published studies of islet cell function reveal unexpected features of
glucagon-like peptide-1 (GLP-1) receptor-mediated signal transduction in the
pancreatic β-cell. Although GLP-1 is established to be a cAMP-elevating ... Cited by 127 - Related articles - BL Direct - All 6 versions
R Mahalingam, N Fedoroff - Physiologia Plantarum, 2003 - huck.psu.edu Introduction Contemporary organisms live in an oxidizing environ- ment and
generate highly reactive partially reduced oxy- gen species while converting
light energy into chemical energy and chemical energy into biomass and ... Cited by 66 - Related articles - View as HTML - BL Direct - All 7 versions
RA Yotter, LA Lee, DM Wilson - IEEE Sensors Journal, 2004 - ee.washington.edu Abstract—A review of optical, chemical, and biological sensors to detect
metabolic activity at the single-cell level is presented in the context of the
development of lab-on-a-chip research instrumentation. The sensors reviewed ... Cited by 51 - Related articles - View as HTML - BL Direct - All 6 versions
- ►nih.gov R Bertram, L Satin, M Zhang, P Smolen, A … - Biophysical journal, 2004 - Elsevier Pancreatic islets of Langerhans produce bursts of electrical activity when
exposed to stimulatory glucose levels. These bursts often have a regular
repeating pattern, with a period of 10–60 s. In some cases, however, the ... Cited by 46 - Related articles - BL Direct - All 15 versions
- ►psu.edu [PDF] R Bertram, A Sherman - Bulletin of mathematical biology, 2004 - Springer Insulin-secreting β-cells, located within the pancreatic islets of Langerhans,
are excitable cells that produce regular bursts of action potentials when
stimulated by glucose. This system has been the focus of mathematical ... Cited by 34 - Related articles - All 6 versions
- ►aspetjournals.org AS Narang, RI Mahato - Pharmacological reviews, 2006 - ASPET Islet transplantation may be used to treat type I diabetes. Despite tremendous
progress in islet isolation, culture, and preservation, the clinical use of this
modality of treatment is limited due to post-transplantation challenges to ... Cited by 32 - Related articles - BL Direct - All 13 versions
DS Luciani, S Misler, KS Polonsky - The Journal of Physiology, 2006 - Physiological Soc Exposure of pancreatic islets of Langerhans to physiological concentrations of
glucose leads to secretion of insulin in an oscillatory pattern. The
oscillations in insulin secretion are associated with oscillations in ... Cited by 26 - Related articles - BL Direct - All 7 versions
- ►endocrinology-journals.org W Wang, L Upshaw, DM Strong, RP … - Journal of Endocrinology, 2005 - Soc Endocrinology In this study, we investigated the use of a novel oxygen biosensor system to
detect changes in oxygen consumption rates (OCRs) by islets in response to
glucose. Islets from non-human primate and human pancreata were seeded into ... Cited by 22 - Related articles - All 3 versions
GM Dahlgren, LM Kauri, RT Kennedy - BBA-General Subjects, 2005 - Elsevier Glucose induces complex patterns of oscillations in intracellular Ca 2+
concentration ([Ca 2+ ] i ), metabolism and secretion in islets of Langerhans
including “slow” and “fast” pulses with period of 2–5 min and ... Cited by 19 - Related articles - All 3 versions
