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Scholar Results 1 - 10 of about 37 citing van Haeften: Disturbances in β-cell function in impaired fasting glycemia. (0.09 sec) 

Type 2 diabetes: principles of pathogenesis and therapy

- harvard.edu [PDF] 
M Stumvoll, BJ Goldstein, TW van Haeften - The Lancet, 2005 - Elsevier
Type 2 diabetes mellitus has become an epidemic, and virtually no physician is
without patients who have the disease. Whereas insulin insensitivity is an early
phenomenon partly related to obesity, pancreas β-cell function declines ...
Cited by 433 - Related articles - All 17 versions

Contributions of β-cell dysfunction and insulin resistance to the pathogenesis of impaired …

- diabetesjournals.org
MA Abdul-Ghani, D Tripathy, RA DeFronzo - Diabetes Care, 2006 - Am Diabetes Assoc
Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) are
intermediate states in glucose metabolism that exist between normal glucose
tolerance and overt diabetes. Epidemiological studies demonstrate that the ...
Cited by 88 - Related articles - BL Direct - All 5 versions

Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose …

- diabetesjournals.org
MA Abdul-Ghani, CP Jenkinson, DK … - Diabetes, 2006 - Am Diabetes Assoc
This study was conducted to observe changes in insulin secretion and insulin
action in subjects with impaired fasting glucose (IFG) and/or impaired glucose
tolerance (IGT). A total of 319 subjects were studied with an oral glucose ...
Cited by 83 - Related articles - BL Direct - All 5 versions

[CITATION] Hierarchy of the beta-cell signals controlling insulin secretion


JC Henquin, MA Ravier, M Nenquin, JC Jonas … - European Journal of Clinical Investigation, 2003 - journals.indexcopernicus.com
logo IndexCopernicus, Current language: English. IC Journals Master List. Journal
of the Week. Journals Master List. Journals from CC list. ...
Cited by 78 - Related articles - BL Direct - All 4 versions

Predominant role of reduced beta-cell sensitivity to glucose over insulin resistance in …


E Ferrannini, A Gastaldelli, Y Miyazaki, M … - Diabetologia, 2003 - Springer
Aims/hypothesis. Impaired glucose tolerance (IGT) is an insulin-resistant state
and a risk factor for Type 2 diabetes. The relative roles of insulin resistance
and insulin deficiency in IGT have been disputed. Methods. In 40 IGT ...
Cited by 60 - Related articles - BL Direct - All 3 versions

[PDF] Insulin-like growth factors and pancreas beta cells


TW Van Haeften, TB Twickler - European journal of clinical investigation, 2004 - igitur-archive.library.uu.nl
Abstract Insulin-like growth factors (IGFs) have been implicated in normal
growth, and especially foetal pancreas beta-cell development. As low birth
weight has been implicated in the development of obesity and type 2 ...
Cited by 30 - Related articles - View as HTML - BL Direct - All 11 versions

Mechanisms of Impaired Fasting Glucose and Glucose Intolerance Induced by a∼ 50% …

- shouxi.net
AV Matveyenko, JD Veldhuis, PC Butler - Diabetes, 2006 - Am Diabetes Assoc
Impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) often
coexist and as such represent a potent risk factor for subsequent development of
type 2 diabetes. β-Cell mass is ∼50% deficient in IFG and ∼65% ...
Cited by 21 - Related articles - BL Direct - All 6 versions

The dipeptidyl peptidase-4 inhibitor vildagliptin improves β-cell function and insulin …

- Free from Publisher
KM Utzschneider, J Tong, B Montgomery, J … - Diabetes care, 2008 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—A total of 22 subjects with IFG (11 female and 11
male, mean ± SD age 59.6 ± 11.5 years) were treated orally with 100 mg
vildagliptin once daily in a single-blind study. Subjects received placebo ...
Cited by 22 - Related articles - BL Direct - All 9 versions

Variations in insulin secretion in carriers of the E23K variant in the KIR6. 2 subunit of the ATP …

- diabetesjournals.org
LM t Hart, TW van Haeften, JM Dekker, M Bot … - Diabetes, 2002 - Am Diabetes Assoc
An association between type 2 diabetes and genetic variation in the KIR6.2 gene
has been reported in several populations. Based on in vitro studies with cell
lines expressing the Glu 23 Lys (E23K) mutation, it was recently suggested ...
Cited by 19 - Related articles - BL Direct - All 6 versions

Early disturbances in insulin secretion in the development of type 2 diabetes mellitus

- uu.nl [PDF] 
TW van Haeften - Molecular and cellular endocrinology, 2002 - Elsevier
After a short description of normal glucose homeostasis, recent findings in
relation to insulin release in three groups with a high risk of future
development of type 2 diabetes are described. Hyperglycemic clamps in ...
Cited by 17 - Related articles - All 6 versions


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