- ►rupress.org L Eliasson, X Ma, E Renstrom, S Barg, PO … - Journal of General Physiology, 2003 - jgp.rupress.org Measurements of membrane capacitance were applied to dissect the cellular
mechanisms underlying PKA-dependent and -independent stimulation of insulin
secretion by cyclic AMP. Whereas the PKA-independent ... Cited by 112 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org ME Doyle, JM Egan - Pharmacological reviews, 2003 - ASPET Blood glucose levels are sensed and controlled by the release of hormones from
the islets of Langerhans in the pancreas. The -cell, the insulin-secreting cell
in the islet, can detect subtle increases in circulating glucose levels and ... Cited by 79 - Related articles - BL Direct - All 8 versions
F Reimann, FM Gribble - Diabetes, 2002 - Am Diabetes Assoc Glucagon-like peptide-1 (GLP-1) is released from intestinal L-cells in response
to carbohydrate and fat in the diet. Despite the interest in GLP-1 as an
antidiabetic agent, very little is known about the mechanism of stimulus- ... Cited by 71 - Related articles - BL Direct - All 5 versions
S Barg - Pharmacology and Toxicology, 2003 - interscience.wiley.com Abstract: In pancreatic B- and A-cells, metabolic stimuli regulate biochemical
and electrical processes that culminate in Ca 2+ -influx and release of insulin
or glucagon, respectively. Like in other (neuro)endocrine cells, Ca 2+ ... Cited by 49 - Related articles - BL Direct - All 7 versions
K Kimoto, K Suzuki, T Kizaki, Y Hitomi, H … - Biochemical and Biophysical Research …, 2003 - Elsevier Oxidative stress is induced under diabetic conditions and possibly causes
various forms of tissue damage in patients with diabetes. Recently, it has
become aware that susceptibility of pancreatic β-cells to oxidative stress ... Cited by 46 - Related articles - All 4 versions
- ►diabetesjournals.org JC Henquin - Diabetes, 2004 - Am Diabetes Assoc Physiologically, insulin secretion is subject to a dual, hierarchal control by
triggering and amplifying pathways. By closing ATP-sensitive K + channels (K ATP
channels) in the plasma membrane, glucose and other metabolized nutrients ... Cited by 37 - Related articles - BL Direct - All 4 versions
- ►physiology.org M Lehtihet, N Welsh, PO Berggren, GA Cook, … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc Hypoglycemic sulfonylureas such as glibenclamide have been widely used to treat
type 2 diabetic patients for 40 yr, but controversy remains about their mode of
action. The widely held view is that they promote rapid insulin exocytosis ... Cited by 26 - Related articles - BL Direct - All 3 versions
P Proks, JD Lippiat - Current pharmaceutical design, 2006 - ingentaconnect.com Abstract: Type-2, or non-insulin-dependent diabetes mellitus is a serious
disease that is now widespread throughout Western society. Glucose intolerance,
or failure of glucose to stimulate insulin secretion, is a primary factor ... Cited by 19 - Related articles - BL Direct - All 4 versions
C Spirlì, R Fiorotto, L Song, J Santos-Sacchi … - Gastroenterology, 2005 - Elsevier Background & Aims: Progressive liver disease is a severe complication of cystic
fibrosis, a genetic disease characterized by impaired epithelial adenosine
3′,5′-cyclic monophosphate-dependent secretion caused by mutations in ... Cited by 12 - Related articles - All 16 versions
J Skalska, G Debska, WS Kunz, A Szewczyk - British journal of pharmacology, 2005 - pubmedcentral.nih.gov Antidiabetic sulphonylureas can bind to various intracellular organelles
including mitochondria. The aim of this study was to monitor the influence of
antidiabetic sulphonylureas on membrane permeability in mitochondria ... Cited by 8 - Related articles - All 4 versions