- ►diabetesjournals.org S Srivastava, HJ Goren - Diabetes, 2003 - Am Diabetes Assoc Four hypotheses have been posited on the role of insulin in glucose-stimulated
insulin secretion; available evidence has supported insulin as being 1)
essential, 2) a positive modulator, 3) a negative modulator, or 4) not ... Cited by 19 - Related articles - BL Direct - All 4 versions
CS Nunemaker, M Zhang, LS Satin - Diabetes, 2004 - Am Diabetes Assoc Recent work suggests that insulin may exert both positive and negative feedback
directly on pancreatic β-cells. To investigate the hypothesis that insulin
modulates β-cell metabolism, mouse islets and β-cell clusters were loaded ... Cited by 15 - Related articles - BL Direct - All 5 versions
DI Shah, M Singh - Molecular and cellular biochemistry, 2007 - Springer (serum homocysteine >10 lM), respectively. Vascular endothelial dysfunction was
assessed using isolated aortic ring prep- aration, electron microscopy of
thoracic aorta and serum concentration of nitrite/nitrate. The expression ... Cited by 13 - Related articles - BL Direct - All 4 versions
PD Borge, J Moibi, SR Greene, M Trucco, RA … - Diabetes, 2002 - Am Diabetes Assoc Glucose is the main physiological secretagogue for insulin secretion by
pancreatic β-cells, and the major biochemical mechanisms involved have been
elucidated. In particular, an increase in intracellular calcium is ... Cited by 11 - Related articles - BL Direct - All 3 versions
- ►physiology.org SM Katzman, MA Messerli, DT Barry, A … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc The cells within the intact islet of Langerhans function as a metabolic
syncytium, secreting insulin in a coordinated and oscillatory manner in response
to external fuel. With increased glucose, the oscillatory amplitude is ... Cited by 7 - Related articles - BL Direct - All 4 versions
DI Shah, M Singh - International journal of cardiology, 2007 - Elsevier Rats were uninephroctomized and DOCA (40 mg kg − 1 , sc) was administered to
rats to produce hypertension (MABP > 140 mm Hg). Vascular endothelial
dysfunction was assessed using isolated aortic ring preparation, electron ... Cited by 2 - Related articles - All 13 versions
HJ Goren - Current Diabetes Reviews, 2005 - ingentaconnect.com Abstract: Diabetes is on the increase worldwide and greater than 90% are type 2.
There are two features to type 2 diabetes: muscle, fat and liver tissues are
insulin resistant and β cells lose the ability to secrete insulin. Prior ... Related articles - BL Direct - All 2 versions