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Scholar Results 1 - 10 of about 55 citing Nesher: Modeling phasic insulin release. (0.09 sec) 

Pharmacological agents that directly modulate insulin secretion

- aspetjournals.org
ME Doyle, JM Egan - Pharmacological reviews, 2003 - ASPET
Blood glucose levels are sensed and controlled by the release of hormones from the islets of
Langerhans in the pancreas. The -cell, the insulin-secreting cell in the islet, can detect subtle
increases in circulating glucose ...
Cited by 82 - Related articles - BL Direct - All 8 versions

[CITATION] Hierarchy of the beta-cell signals controlling insulin secretion


JC Henquin, MA Ravier, M Nenquin, … - … Journal of Clinical …, 2003 - journals.indexcopernicus.com
logo IndexCopernicus, Current language: English. IC Journals Master List. Journal of the Week. Journals
Master List. Journals from CC list. Recently Added Journals. Top 100 Journals. Publishers. Top 20
Publishers. Journal Search. Evaluation methodology. IC Journals Master List 2008. ...
Cited by 79 - Related articles - BL Direct - All 4 versions

First-phase insulin secretion: does it exist in real life? Considerations on shape and …

- physiology.org
A Caumo, L Luzi - American Journal of Physiology- Endocrinology …, 2004 - Am Physiological Soc
To fulfill its preeminent function of regulating glucose metabolism, insulin secretion must not only
be quantitatively appropriate but also have qualitative, dynamic properties that optimize insulin
action on target tissues. This ...
Cited by 42 - Related articles - All 3 versions

In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse


JC Henquin, M Nenquin, P Stiernet, B Ahren - Diabetes, 2006 - Am Diabetes Assoc
The mechanisms underlying biphasic insulin secretion have not been completely elucidated. We
compared the pattern of plasma insulin changes during hyperglycemic clamps in mice to that of
glucose-induced insulin secretion ...
Cited by 36 - Related articles - BL Direct - All 5 versions

The Role of Voltage-Gated Calcium Channels in Pancreatic {beta}-Cell Physiology …

- endojournals.org
SN Yang, PO Berggren - Endocrine reviews, 2006 - Endocrine Soc
Voltage-gated calcium (Ca V ) channels are ubiquitously expressed in various cell types throughout
the body. In principle, the molecular identity, biophysical profile, and pharmacological property of
Ca V channels are independent of ...
Cited by 34 - Related articles - BL Direct - All 6 versions

Evaluation of insulin sensitivity and β-cell function indexes obtained from minimal …


GM Steil, C Hwu, R Janowski, F Hariri, S Jinagouda, C … - Diabetes, 2004 - Am Diabetes Assoc
Modeling analysis of glucose, insulin, and C-peptide following a meal has been proposed as a means
to estimate insulin sensitivity (S i ) and β-cell function from a single test. We compared the
model-derived meal indexes with ...
Cited by 25 - Related articles - BL Direct - All 4 versions

Acute plasma glucose increase, but not early insulin response, regulates plasma …

- eje-online.org [PDF] 
L Briatore, G Andraghetti, R Cordera - European Journal of Endocrinology, 2003 - EFES
Objective: The independent role of glucose and insulin in ghrelin regulation is still controversial;
this is also because in healthy subjects it is difficult to isolate the increase of glucose from
that of insulin. The aim of this ...
Cited by 23 - Related articles - BL Direct - All 8 versions

Stimulation of insulin release by glucose is associated with an increase in the …


SG Straub, G Shanmugam, GWG Sharp - Diabetes, 2004 - Am Diabetes Assoc
Electron microscopy and quantitative stereological techniques were used to study the dynamics of the
docked granule pool in the rat pancreatic β-cell. The mean number of granules per β-cell was
11,136. After equilibration in RPMI ...
Cited by 23 - Related articles - BL Direct - All 5 versions

Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose …

- physiology.org
SG Straub, GWG Sharp - American Journal of Physiology- Cell …, 2004 - Am Physiological Soc
The biphasic secretory response of pancreatic -cells to abrupt and sustained exposure to glucose is
well documented. Some of the ATP-sensitive K + (K ATP ) channel-dependent mechanisms underlying the
first phase of insulin release are ...
Cited by 22 - Related articles - All 3 versions

Syntaxin 4 Facilitates Biphasic Glucose-Stimulated Insulin Secretion from …

- endojournals.org
BA Spurlin, DC Thurmond - Molecular Endocrinology, 2006 - Endocrine Soc
Numerous overexpression studies have recently implicated Syntaxin 4 as an effector of insulin
secretion, although its requirement in insulin granule exocytosis is unknown. To address this,
islets from Syntaxin 4 heterozygous ...
Cited by 22 - Related articles - BL Direct - All 4 versions


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