P Rorsman, E Renström - Diabetologia, 2003 - Springer Glucose-induced insulin secretion in response to a step increase in blood glucose concentrations
follows a bi- phasic time course consisting of a rapid and transient first phase followed by a slowly
developing and sus- tained second phase. Because Type 2 diabetes involves defects of ... Cited by 205 - Related articles - BL Direct - All 3 versions
- ►endojournals.org E Ferrannini, A Gastaldelli, Y Miyazaki, M … - Journal of Clinical …, 2005 - Endocrine Soc The nature of the progressive ß-cell failure occurring as normal glucose tolerant (NGT) individuals
progress to type 2 diabetes (T2DM) is incompletely understood. We measured insulin sensitivity
(by a euglycemic insulin clamp) and insulin secretion rate (by deconvolution of plasma C- ... Cited by 133 - Related articles - All 5 versions
- ►rupress.org L Eliasson, X Ma, E Renstrom, S Barg, PO … - Journal of General …, 2003 - jgp.rupress.org Measurements of membrane capacitance were applied to dissect the cellular mechanisms underlying
PKA-dependent and -independent stimulation of insulin secretion by cyclic AMP. Whereas the
PKA-independent (Rp-cAMPS–insensitive) component correlated with a rapid increase in ... Cited by 114 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] T Tsuboi, G da Silva Xavier, GG Holz, LS … - Biochemical …, 2003 - pubmedcentral.nih.gov Takashi TSUBOI*, Gabriela DA SILVA XAVIER*, George G. HOLZ†, Laurence S.
JOUAVILLE‡, Andrew P. THOMAS‡ and Guy A. RUTTER*1 *Henry Wellcome Laboratories for
Integrated Cell Signalling, Department of Biochemistry, School of Medical Sciences, ... Cited by 85 - Related articles - BL Direct - All 23 versions
JC Henquin, MA Ravier, M Nenquin, … - … Journal of Clinical …, 2003 - journals.indexcopernicus.com logo IndexCopernicus, Current language: English. IC Journals Master List. Journal of the Week.
Journals Master List. Journals from CC list. Recently Added Journals. Top 100 Journals.
Publishers. Top 20 Publishers. Journal Search. Evaluation methodology. ... Cited by 79 - Related articles - BL Direct - All 4 versions
E Ferrannini, A Mari - Diabetologia, 2004 - Springer The importance of both insulin resistance and beta cell dysfunction in the pathogenesis of glucose
intolerance is widely recognised. Also popular is the concept that beta cell secretory function
must be viewed in the context of extant insulin resistance. This For Debate moves from ... Cited by 76 - Related articles - BL Direct - All 4 versions
K Gerozissis - Cellular and Molecular Neurobiology, 2003 - Springer SUMMARY 1. While many questions remain unanswered, it is now well documented that, contrary
to earlier views, insulin is an important neuromodulator, contributing to neurobiological
processes, in particular energy homeostasis and cognition. A specific role on cognitive ... Cited by 77 - Related articles - BL Direct - All 6 versions
X Geng, L Li, S Watkins, PD Robbins, P Drain - Diabetes, 2003 - Am Diabetes Assoc With ATP sites on K ir 6.2 that inhibit activity and ADP sites on SUR1 that antagonize the
inhibition, ATP-sensitive potassium channels (K ATP channels) are designed as exquisite sensors
of adenine nucleotide levels that signal changes in glucose metabolism. If pancreatic K ... Cited by 63 - Related articles - BL Direct - All 4 versions
- ►endojournals.org HJ Goren, RN Kulkarni, CR Kahn - Endocrinology, 2004 - Endocrine Soc Transgenic mice phenotypes generally depend on the background strains used in their
creation. To examine the effects of genetic background on insulin signaling, we analyzed glucose
homeostasis in four inbred strains of mice [C57BL/6 (B6), C57BLKS/6 (KLS), DBA/2 ... Cited by 50 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org JC Henquin - Diabetes, 2004 - Am Diabetes Assoc Physiologically, insulin secretion is subject to a dual, hierarchal control by triggering and amplifying
pathways. By closing ATP-sensitive K + channels (K ATP channels) in the plasma
membrane, glucose and other metabolized nutrients depolarize β-cells, stimulate Ca 2+ ... Cited by 37 - Related articles - BL Direct - All 4 versions
