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Scholar Results 1 - 10 of about 22 citing Newgard: Stimulus/Secretion Coupling Factors in Glucose-Stimulated Insulin Secretion. (0.09 sec) 

Differential effects of glucose and lactate on glucosensing neurons in the ventromedial …

- diabetesjournals.org
Z Song, VH Routh - Diabetes, 2005 - Am Diabetes Assoc
Glucose directly alters the action potential frequency of glucosensing neurons
in the ventromedial hypothalamic nucleus (VMN). Glucose-excited neurons
increase, and glucose-inhibited neurons decrease, their action potential ...
Cited by 61 - Related articles - All 7 versions

A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase …

- shouxi.net
SM Ronnebaum, O Ilkayeva, SC Burgess, JW … - Journal of Biological Chemistry, 2006 - ASBMB
Glucose-stimulated insulin secretion (GSIS) from pancreatic islet β-cells is
central to control of mammalian fuel homeostasis. Glucose metabolism mediates
GSIS in part via ATP-regulated K + (K ATP ) channels, but multiple lines of ...
Cited by 41 - Related articles - All 5 versions

Reactive oxygen species as a signal in glucose-stimulated insulin secretion

- shouxi.net
J Pi, Y Bai, Q Zhang, V Wong, LM Floering, K … - Diabetes, 2007 - Am Diabetes Assoc
One of the unique features of β-cells is their relatively low expression of
many antioxidant enzymes. This could render β-cells susceptible to oxidative
damage but may also provide a system that is sensitive to reactive oxygen ...
Cited by 35 - Related articles - BL Direct - All 6 versions

M ETABOLIC E NGINEERING: Advances in Modeling and Intervention in Health and …


ML Yarmush, S Banta - Annual Review of Biomedical Engineering, 2003 - Annual Reviews
▪ Abstract The field of metabolic engineering encompasses a powerful set of
tools that can be divided into (a) methods to model complex metabolic pathways
and (b) techniques to manipulate these pathways for a desired metabolic ...
Cited by 29 - Related articles - BL Direct - All 4 versions

Insulin-secreting cells derived from stem cells: clinical perspectives, hypes and hopes


E Roche, JA Reig, A Campos, B Paredes, JR … - Transplant immunology, 2005 - Elsevier
Diabetes is a degenerative disease that results from the selective destruction
of pancreatic β-cells. These cells are responsible for insulin production and
secretion in response to increases in circulating concentrations of ...
Cited by 24 - Related articles - All 3 versions

Increased oxygen consumption rates in response to high glucose detected by a novel …

- endocrinology-journals.org
W Wang, L Upshaw, DM Strong, RP … - Journal of Endocrinology, 2005 - Soc Endocrinology
In this study, we investigated the use of a novel oxygen biosensor system to
detect changes in oxygen consumption rates (OCRs) by islets in response to
glucose. Islets from non-human primate and human pancreata were seeded into ...
Cited by 21 - Related articles - All 3 versions

[PDF] Fuel sensing and the central nervous system (CNS): implications for the regulation of energy …


RJ Seeley, DA York - Obesity Reviews, 2005 - iaso.org
Blackwell Science, LtdOxford, UKOBRobesity reviews1467-78812005 The
International Association for the Study of Obesity. 63259265Review ArticleFuel
sensing and the CNS RJ Seeley & DA York ... Address reprint requests to: ...
Cited by 16 - Related articles - View as HTML - BL Direct - All 5 versions

[PDF] L-alanine induces changes in metabolic and signal transduction gene expression in a clonal …


GA Cunningham, NH McClenaghan, PR Flatt … - Clinical Science, 2005 - cs.portlandpress.com
Acute effects of nutrient stimuli on pancreatic β-cell function are widely
reported; however, the chronic effects of insulinotropic amino acids, such as
L-alanine, on pancreatic β-cell function and integrity are unknown. In the ...
Cited by 11 - Related articles - View as HTML - BL Direct - All 9 versions

Mitochondrial regulation of insulin production in rat pancreatic islets


G Leibowitz, MZ Khaldi, A Shauer, M Parnes, … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 1549–1559 DOI 10.1007/s00125-005-1811-6 ARTICLE
G. Leibowitz . MZ Khaldi . A. Shauer . M. Parnes . AI Oprescu . E. Cerasi . ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Inositol hexakisphosphate and sulfonylureas regulate β-cell protein phosphatases


M Lehtihet, RE Honkanen, Å Sjöholm - Biochemical and Biophysical Research …, 2004 - Elsevier
In human type 2 diabetes, loss of glucose-stimulated insulin exocytosis from the
pancreatic β-cell is an early pathogenetic event. Mechanisms controlling
insulin exocytosis are, however, not fully understood. We show here that ...
Cited by 6 - Related articles - All 5 versions


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