RM Seaberg, SR Smukler, TJ Kieffer, G … - Nature Biotechnology, 2004 - utoronto.ca The clonal isolation of putative adult pancreatic precursors has been an elusive
goal of researchers seeking to develop cell replacement strategies for diabetes.
We report the clonal identification of multipotent precursor cells from the ... Cited by 263 - Related articles - BL Direct - All 13 versions
- ►endojournals.org L Farilla, A Bulotta, B Hirshberg, S Li Calzi, … - Endocrinology, 2003 - Endocrine Soc The peptide hormone, glucagon-like peptide 1 (GLP-1), has been shown to increase
glucose-dependent insulin secretion, enhance insulin gene transcription, expand
islet cell mass, and inhibit ß-cell apoptosis in animal models of ... Cited by 218 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org K Wynne, S Stanley, B McGowan, S Bloom - Journal of Endocrinology, 2005 - Soc Endocrinology Our understanding of the physiological systems that regulate food intake and
body weight has increased immensely over the past decade. Brain centres,
including the hypothalamus, brainstem and reward centres, signal via ... Cited by 173 - Related articles - All 4 versions
A Hirasawa, K Tsumaya, T Awaji, S Katsuma, … - Nature medicine, 2005 - bioweb.usu.edu Diabetes, a disease in which the body does not produce or use insulin properly,
is a serious global health problem1–3. Gut polypeptides secreted in response
to food intake, such as glucagon-like peptide-1 (GLP-1), are potent ... Cited by 159 - Related articles - View as HTML - All 9 versions
- ►physiology.org S Seino, T Shibasaki - Physiological reviews, 2005 - Am Physiological Soc Stimulus-secretion coupling is an essential process in secretory cells in which
regulated exocytosis occurs, including neuronal, neuroendocrine, endocrine, and
exocrine cells. While an increase in intracellular Ca 2+ concentration ([Ca ... Cited by 146 - Related articles - BL Direct - All 4 versions
- ►physiology.org S Stanley, K Wynne, B McGowan, S Bloom - Physiological reviews, 2005 - Am Physiological Soc Our knowledge of the physiological systems controlling energy homeostasis has
increased dramatically over the last decade. The roles of peripheral signals
from adipose tissue, pancreas, and the gastrointestinal tract reflecting ... Cited by 88 - Related articles - BL Direct - All 7 versions
- ►bcell.org [PDF] PE MacDonald, MB Wheeler - Diabetologia, 2003 - Springer Insulin secretion from pancreatic islet beta cells is acutely regulated by a
complex interplay of metabolic and electrogenic events. The electrogenic
mechanism regulating insulin secretion from beta cells is com- monly ... Cited by 74 - Related articles - BL Direct - All 4 versions
J Sturis, CF Gotfredsen, J Rømer, B Rolin, … - British journal of pharmacology, 2003 - pubmedcentral.nih.gov When liraglutide was dosed sc at 150 μg kg −1 bid for 6 weeks in ZDF rats
6–8 weeks of age at study start, diabetes development was markedly attenuated.
Blood glucose was approximately 12 mM lower compared to vehicle (P<0.0002), ... Cited by 71 - Related articles - BL Direct - All 4 versions
E Muscelli, G Mingrone, S Camastra, M Manco, … - The American journal of medicine, 2005 - Elsevier At baseline, patients were hyperinsulinemic (194 ± 47 pmol/L vs. 55 ± 25
pmol/L, P < 0.0001), hypertriglyceridemic (1.56 ± 0.30 mmol/L vs. 0.78 ± 0.32
mmol/L, P < 0.0001), and profoundly insulin resistant (insulin-mediated ... Cited by 60 - Related articles - All 15 versions
PL Brubaker, Y Anini - Canadian journal of physiology and pharmacology, 2003 - article.pubs.nrc-cnrc.gc.ca Abstract: The proglucagon-derived peptide family consists of three highly
related peptides, glucagon and the glucagon-like peptides GLP-1 and GLP-2.
Although the biological activity of glucagon as a counter-regulatory ... Cited by 49 - Related articles - BL Direct - All 9 versions
