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Scholar Results 1 - 10 of about 51 citing Unno: Production and Characterization of Reg Knockout Mice. (0.15 sec) 

Differentially expressed proteins in the pancreas of diet-induced diabetic mice

- mcponline.org
L Qiu, EO List, JJ Kopchick - Molecular & Cellular Proteomics, 2005 - ASBMB
The pancreas is a heterogeneous organ mixed with both exocrine and endocrine cells. The pancreas
is involved in metabolic activities with the endocrine cells participating in the regulation of blood
glucose, while the exocrine portion provides a compatible environment for the pancreatic ...
Cited by 33 - Related articles - BL Direct - All 4 versions

The a3 isoform of V-ATPase regulates insulin secretion from pancreatic {beta}-cells

- biologists.org
GH Sun-Wada, T Toyomura, Y Murata, A … - Journal of cell …, 2006 - jcs.biologists.org
Vacuolar-type H + -ATPase (V-ATPase) is a multi-subunit enzyme that has important roles in
the acidification of a variety of intracellular compartments and some extracellular milieus. Four
isoforms for the membrane-intrinsic subunit (subunit a) of the V-ATPase have been ...
Cited by 26 - Related articles - BL Direct - All 5 versions

Molecular cloning, expression and chromosomal localization of a novel human …


K Nata, Y Liu, L Xu, T Ikeda, T Akiyama, N Noguchi, S … - Gene, 2004 - Elsevier
Regenerating gene (Reg), first isolated from a regenerating islet cDNA library [J. Biol. Chem.
263 (1988) 2111], encodes a secretory protein with a growth stimulating effect on pancreatic
β cells that ameliorates the diabetes of 90% depancreatized rats [Proc. Natl. Acad. Sci. ...
Cited by 20 - Related articles - All 3 versions

The multifunctional family of secreted proteins containing a C-type lectin-like …


JL Iovanna, JC Dagorn - BBA-General Subjects, 2005 - Elsevier
PSP/Lithostathine/PTP/regI, PAP/p23/HIP, reg1L, regIV and “similar to PAP” are the members
of a multifunctional family of secreted proteins containing a C-type lectin-like domain linked to
a short N-terminal peptide. The expression of this group of proteins is controlled by ...
Cited by 22 - Related articles - All 4 versions

Dynamic interaction between T cell-mediated beta cell damage and beta cell repair …

- physiology.org [PDF] 
SS Vukkadapu, JM Belli, K Ishii, AG Jegga, … - Physiological …, 2005 - Am Physiological Soc
Page 1. Dynamic interaction between T cell-mediated beta cell damage and beta cell repair
in the run-up to autoimmune diabetes of the NOD mouse Sankaranand S. Vukkadapu 1 ,
Jenine M. Belli 1 , Koji Ishii 1 , Anil G. Jegga 2 John J. Hutton 2 , ...
Cited by 21 - Related articles - All 4 versions

Exocrine meets endocrine: pancreatic stone protein and regenerating protein—two …


R Graf, M Schiesser, T Reding, P Appenzeller, LK … - Journal of Surgical …, 2006 - Elsevier
For PSP/reg, a role in proliferation and regeneration of islet cells has been postulated. A hitherto
insufficiently understood phenomenon is the massive up-regulation of PSP/reg in pancreatic
tissue and juice under conditions of stress. Similarly, PAP (pancreatitis-associated ...
Cited by 21 - Related articles - All 22 versions

INGAP peptide improves nerve function and enhances regeneration in …

- fasebj.org [PDF] 
J Tam, L Rosenberg, D Maysinger - The FASEB Journal, 2004 - FASEB
The FASEB Journal express article10.1096/fj.04-1894fje. Published online September 2,
2004. ... INGAP peptide improves nerve function and enhances ... Joseph Tam,* Lawrence
Rosenberg, † and Dusica Maysinger* ... Corresponding author: Dusica Maysinger, ...
Cited by 18 - Related articles - BL Direct - All 4 versions

IL-21 signaling is critical for the development of type I diabetes in the NOD mouse


R Spolski, M Kashyap, C Robinson, Z Yu, … - Proceedings of the …, 2008 - National Acad Sciences
IL-21 is a pleiotropic type I cytokine that shares the common cytokine receptor γ chain and plays
important roles for normal Ig production, terminal B cell differentiation to plasma cells, and Th17
differentiation. IL-21 is elevated in several autoimmune diseases, and blocking its action ...
Cited by 21 - Related articles - All 8 versions

Acidic duodenal pH alters gene expression in the cystic fibrosis mouse pancreas

- physiology.org
S Kaur, O Norkina, D Ziemer, LC … - American Journal of …, 2004 - Am Physiological Soc
The duodenum is abnormally acidic in cystic fibrosis (CF) due to decreased bicarbonate ion
secretion that is dependent on the CF gene product CFTR. In the CFTR null mouse, the acidic
duodenum results in increased signaling from the intestine to the exocrine pancreas in an ...
Cited by 16 - Related articles - BL Direct - All 4 versions

Autoimmunity and Cell Regeneration in Mouse and Human Type 1 Diabetes


… , NA SHERRY, JA KUSHNER, KC HEROLD - Annals of the New …, 2007 - ingentaconnect.com
Accumulating data from animal models of type 1 diabetes and some findings from clinical studies
suggest that autoimmune destruction of islet β cells is associated with enhanced β cell
regeneration. Successful immune therapies, aimed at preservation of islet cell mass, ...
Cited by 15 - Related articles - BL Direct - All 4 versions


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