- ►diabetesjournals.org MR Rickels, MH Schutta, JF Markmann, CF … - Diabetes, 2005 - Am Diabetes Assoc Islet transplantation can provide metabolic stability for patients with type 1
diabetes; however, more than one donor pancreas is usually required to achieve
insulin independence. To evaluate possible mechanistic defects underlying ... Cited by 55 - Related articles - All 6 versions
- ►nih.gov F Souza, N Simpson, A Raffo, C Saxena, A … - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig 1 Department of Medicine and 2 Department of Radiology, Columbia University
Medical Center, New York, New York, USA. 3 Institute of Genetics and Biophysics
“Adriano Buzzati-Traverso,” Consiglio Nazionale delle Ricerche, Naples, ... Cited by 45 - Related articles - BL Direct - All 9 versions
MO Larsen, B Rolin - ILAR JOURNAL., 2004 - dels.nas.edu Animal models of type 1 diabetes remain essential tools for investigation of the
etiology and pathogenesis of the disease and, importantly, for the development
of effective new treatments. Although a range of well-characterized and ... Cited by 38 - Related articles - View as HTML - BL Direct - All 2 versions
RP Robertson - Diabetes, 2004 - Am Diabetes Assoc Whether evaluating long-term success of pancreas or islet transplantation, the
essential information regarding health of the transplant evolves from studies of
β-cell function and insulin secretory reserve. Stimulation of insulin ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org AV Matveyenko, PC Butler - Diabetes, 2006 - Am Diabetes Assoc Type 2 diabetes is characterized by defects in insulin secretion and action and
is preceded by impaired fasting glucose (IFG). The islet anatomy in IFG and type
2 diabetes reveals an ∼50 and 65% deficit in β-cell mass, with increased ... Cited by 39 - Related articles - BL Direct - All 4 versions
- ►endojournals.org RA Ritzel, JB Hansen, JD Veldhuis, PC Butler - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc In health, most insulin is secreted in pulses. Type 2 diabetes mellitus (TTDM)
is characterized by impaired pulsatile insulin secretion with a defect in
insulin pulse mass. It has been suggested that this defect is partly due to ... Cited by 35 - Related articles - BL Direct - All 5 versions
S Del Prato, WJ Wishner, J Gromada, BJ … - Diabetes, Obesity and Metabolism, 2004 - diabetes.org.br Prospective studies have shown that insulin resistance (IR) and impaired insulin
secretion are independent pre- decessors and predictors of overt diabetes in
genetically predisposed individuals [1–3]. Studies involving sub- jects ... Cited by 24 - Related articles - View as HTML - BL Direct - All 6 versions
DK Arulmozhi, A Veeranjaneyulu, SL … - Indian Journal of Pharmacology, 2004 - Medknow Diabetes mellitus is a group of syndromes characterized by hyperglycemia,
altered metabolism of lipids, carbohydrates and protein and an increased risk of
complication of vascular diseases. Type 2 diabetes mellitus is ... Cited by 23 - Related articles - Cached - BL Direct - All 10 versions
- ►bentham.org [PDF] F Souza, M Freeby, K Hultman, N Simpson, A … - Current medicinal chemistry, 2006 - ingentaconnect.com 1 Department of Medicine, Columbia University Medical Center, New York, NY
10032, USA 2 Department of Applied Physics and Applied Mathematics, Columbia
University, New York, NY 10032, USA 3 Department of Radiology, Columbia ... Cited by 20 - Related articles - BL Direct - All 7 versions
- ►physiology.org MO Larsen, CB Juhl, N Porksen, CF Gotfredsen … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Herein, we bridge -cell function and morphology in minipigs. We hypothesized
that different aspects of -cell dysfunction are present in obesity and obesity
with reduced -cell mass by using pulsatile insulin secretion as an early ... Cited by 13 - Related articles - All 4 versions
