DB Carr, KM Utzschneider, RL Hull, K Kodama, BM … - Diabetes, 2004 - Am Diabetes Assoc The underlying pathophysiology of the metabolic syndrome is the subject of debate, with both
insulin resistance and obesity considered as important factors. We evaluated the differential
effects of insulin resistance and central body fat distribution in determining the metabolic ... Cited by 348 - Related articles - BL Direct - All 5 versions
MP Reilly, DJ Rader - Circulation, 2003 - Am Heart Assoc The prevalence of obesity has risen dramatically in the United States. 1 This has led to a marked
increase in the metabolic syndrome (MetSyn), a clustering of atherosclerotic cardiovascular disease
risk factors characterized by visceral adiposity, insulin resistance, low HDL cholesterol ... Cited by 265 - Related articles - BL Direct - All 7 versions
- ►asnjournals.org BE Wisse - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol The metabolic effects of obesity have made this highly prevalent disease one of the most common
risk factors for diabetes, hypertension, and atherosclerosis, the leading causes of end-stage
renal failure. However, obesity per se, as defined by body mass index, is less predictive of ... Cited by 226 - Related articles - BL Direct - All 6 versions
- ►physiology.org DE Kelley, TM McKolanis, RAF Hegazi, … - American Journal of …, 2003 - Am Physiological Soc The current study was undertaken to examine metabolic and body composition correlates of
fatty liver in type 2 diabetes mellitus (DM). Eighty-three men and women with type 2 DM [mean
body mass index (BMI): 34 ± 0.5 kg/m 2 ] and without clinical or laboratory evidence of ... Cited by 196 - Related articles - BL Direct - All 3 versions
- ►endojournals.org KM Utzschneider, SE Kahn - Journal of Clinical Endocrinology & …, 2006 - Endocrine Soc Evidence Synthesis: Insulin resistance in NAFLD is characterized by reductions in
whole-body, hepatic, and adipose tissue insulin sensitivity. The mechanisms underlying the accumulation
of fat in the liver may include excess dietary fat, increased delivery of free fatty acids to the ... Cited by 116 - Related articles - BL Direct - All 4 versions
M Adiels, MR Taskinen, C Packard, MJ Caslake, A … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 755–765 DOI 10.1007/s00125-005-0125-z ARTICLE M.
Adiels . M.-R. Taskinen . C. Packard . MJ Caslake . A. Soro-Paavonen . J. Westerbacka . S.
Vehkavaara . A. Häkkinen . S.-O. Olofsson . H. Yki-Järvinen . J. Borén ... Cited by 116 - Related articles - BL Direct - All 5 versions
JD Brunzell, AF Ayyobi - The American journal of medicine, 2003 - Elsevier Patients with type 2 diabetes mellitus or the metabolic syndrome have a unique dyslipidemia
characterized by hypertriglyceridemia; elevated blood levels of apolipoprotein B; small, dense
low-density lipoprotein (LDL) cholesterol; and low levels of high-density lipoprotein (HDL) ... Cited by 80 - Related articles - All 9 versions
- ►physiology.org CA Slentz, LB Aiken, JA Houmard, CW … - Journal of Applied …, 2005 - Am Physiological Soc Despite the importance of randomized, dose-response studies for proper evaluation of effective
clinical interventions, there have been no dose-response studies on the effects of exercise amount
on abdominal obesity, a major risk factor for metabolic syndrome, diabetes, and ... Cited by 79 - Related articles - BL Direct - All 8 versions
- ►ahajournals.org JP Despres, I Lemieux, J Bergeron, P Pibarot, … - … , and vascular biology, 2008 - Am Heart Assoc From the Hôpital Laval Research Centre (J.-PD, IL, P. Pibarot, PM, EL, JR-C., OFB, P.
Poirier); the Institut universitaire de cardiologie et de pneumologie (J.-PD, PM, EL, JR-C.,
OFB, P. Poirier), Hôpital Laval; the Division of Kinesiology (J.-PD), Department of Social ... Cited by 78 - Related articles - All 9 versions
AF Ayyobi, JD Brunzell - The American journal of cardiology, 2003 - Elsevier Metabolic abnormalities associated with the metabolic syndrome are also present in patients
with type 2 diabetes mellitus and in those with familial combined hyperlipidemia (FCHL). These
abnormalities include central obesity, insulin resistance with hyperinsulinemia, ... Cited by 78 - Related articles - All 10 versions